QPRT Antibody (1C10)

Images

 
Western Blot: QPRT Antibody (1C10) [NBP2-02860] Analysis of extracts (35ug) from 9 different cell lines by using anti-QPRT monoclonal antibody.
Immunocytochemistry/ Immunofluorescence: QPRT Antibody (1C10) [NBP2-02860] - Staining of COS7 cells transiently transfected by pCMV6-ENTRY QPRT.
Immunohistochemistry-Paraffin: QPRT Antibody (1C10) [NBP2-02860] - Staining of paraffin-embedded Human prostate tissue using anti-QPRT mouse monoclonal antibody.
Flow Cytometry: QPRT Antibody (1C10) [NBP2-02860] - HEK293T cells transfected with either overexpression plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-QPRT antibody, and then analyzed ...read more
Western Blot: QPRT Antibody (1C10) [NBP2-02860] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY QPRT (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ...read more
Immunohistochemistry-Paraffin: QPRT Antibody (1C10) [NBP2-02860] - Staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-QPRT mouse monoclonal antibody.
Immunohistochemistry-Paraffin: QPRT Antibody (1C10) [NBP2-02860] - Staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-QPRT mouse monoclonal antibody.
Immunohistochemistry-Paraffin: QPRT Antibody (1C10) [NBP2-02860] - Staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-QPRT mouse monoclonal antibody.
Immunohistochemistry-Paraffin: QPRT Antibody (1C10) [NBP2-02860] - Staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-QPRT mouse monoclonal antibody.
Immunohistochemistry-Paraffin: QPRT Antibody (1C10) [NBP2-02860] - Staining of paraffin-embedded Human endometrium tissue using anti-QPRT mouse monoclonal antibody.
Immunohistochemistry-Paraffin: QPRT Antibody (1C10) [NBP2-02860] - Staining of paraffin-embedded Human liver tissue using anti-QPRT mouse monoclonal antibody.
Immunohistochemistry-Paraffin: QPRT Antibody (1C10) [NBP2-02860] - Staining of paraffin-embedded Human lymphoma tissue using anti-QPRT mouse monoclonal antibody.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, ICC/IF, IHC, IHC-P
Clone
1C10
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

QPRT Antibody (1C10) Summary

Immunogen
Full length human recombinant protein of human QPRT (NP_055113) produced in HEK293T cell.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
QPRT
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-2000
  • Flow Cytometry 1:100
  • Immunocytochemistry/Immunofluorescence 1:100
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:150

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for QPRT Antibody (1C10)

  • EC 2.4.2.19
  • nicotinate-nucleotide pyrophosphorylase (carboxylating)
  • QAPRTase
  • QPRTasenicotinate-nucleotide pyrophosphorylase [carboxylating]
  • Quinolinate phosphoribosyltransferase [decarboxylating]
  • quinolinate phosphoribosyltransferase

Background

This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. [provided by RefSeq]. COMPLETENESS: complete on the 3' end.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol QPRT
Entrez