PYX/Pyrexia Antibody

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Product Details

Summary
Product Discontinued
View other related PYX/Pyrexia Primary Antibodies

Order Details


    • Catalog Number
      NB100-98760
    • Availability
      Product Discontinued

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PYX/Pyrexia Antibody Summary

Immunogen
A synthetic peptide from 1t cytoplasmic loop of drosophila PYX/Pyrexia conjugated to an immunogenic carrier protein was used as the immunogen.
Specificity
PYX/Pyrexia.
Clonality
Polyclonal
Host
Rabbit
Purity
Unpurified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:300-1:5000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Whole antisera
Preservative
No Preservative
Concentration
LYOPH
Purity
Unpurified
Reconstitution Instructions
Reconstitute with 0.1 ml sterilized water to desired concentration.

Alternate Names for PYX/Pyrexia Antibody

  • Pyrexia receptor
  • Transient channel pyrexia
  • Transient receptor potential channel pyrexia

Background

FUNCTION: Receptor-activated non-selective cation channel involved in protection or tolerance from high temperature stress. Activated by temperatures above 40 degrees Celsius. More permeable to K(+) than to Na(+). May act in stress protection allow flies to survive in natural environments.; SUBUNIT: Homooligomer; between isoform A and isoform B. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: Expressed in various peripheral nerves and the central nerves in embryos. In adults, it is expressed in sensory neurons lying beneath the bristles around eyes, neurons innervating the bristles on the back of thorax and neurons in maxillary palps, proboscis and antennae. Expressed in multidendritic neurons, which mediate temperature sensing, as well as non-multidendritic neurons in larval epidermis. Localizes ubiquitously throughout neurites.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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