PTP1B/PTPN1 Antibody (OTI1C5)


Western Blot: PTPN1 Antibody (1C5) [NBP2-01055] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PTPN1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates more
Immunohistochemistry-Paraffin: PTPN1 Antibody (1C5) [NBP2-01055] Staining of paraffin-embedded Human tonsil using anti-PTPN1 mouse monoclonal antibody.
Immunohistochemistry-Paraffin: PTPN1 Antibody (1C5) [NBP2-01055] - Staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-PTPN1 mouse monoclonal antibody.

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PTP1B/PTPN1 Antibody (OTI1C5) Summary

Full length human recombinant protein of human PTPN1(NP_002818) produced in HEK293T cell.
Immunogen affinity purified
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  • Western Blot 1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:150
Positive Control
PTP1B/PTPN1 Lysate (NBP2-64957)

Reactivity Notes


Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
0.02% Sodium Azide
Immunogen affinity purified

Alternate Names for PTP1B/PTPN1 Antibody (OTI1C5)

  • EC
  • protein tyrosine phosphatase 1B
  • protein tyrosine phosphatase, non-receptor type 1
  • Protein-tyrosine phosphatase 1B
  • PTP1B
  • PTP-1B
  • PTP1Bprotein tyrosine phosphatase, placental
  • PTPN1
  • tyrosine-protein phosphatase non-receptor type 1


The protein encoded by this gene is the founding member of the protein tyrosine phosphatase (PTP) family, which was isolated and identified based on its enzymatic activity and amino acid sequence. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP has been shown to act as a negative regulator of insulin signaling by dephosphorylating the phosphotryosine residues of insulin receptor kinase. This PTP was also reported to dephosphorylate epidermal growth factor receptor kinase, as well as JAK2 and TYK2 kinases, which implicated the role of this PTP in cell growth control, and cell response to interferon stimulation. [provided by RefSeq].


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Positive Control Lysate(s)

Secondary Antibodies


Isotype Controls

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Gene Symbol PTPN1