PTP epsilon Antibody (4G2)

Images

 
Western Blot: PTP epsilon Antibody (4G2) [NBP2-02451] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PTP epsilon (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of ...read more
Immunocytochemistry/ Immunofluorescence: PTP epsilon Antibody (4G2) [NBP2-02451] Staining of COS7 cells transiently transfected by pCMV6-ENTRY PTP epsilon.
Flow Cytometry: PTP epsilon Antibody (4G2) [NBP2-02451] - HEK293T cells transfected with either overexpression plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-PTP epsilon antibody, and ...read more
Flow Cytometry: PTP epsilon Antibody (4G2) [NBP2-02451] - Analysis of Hela cells, using anti-PTP epsilon antibody, (Red), compared to a nonspecific negative control antibody (Blue).
Flow Cytometry: PTP epsilon Antibody (4G2) [NBP2-02451] - Analysis of Jurkat cells, using anti-PTP epsilon antibody, (Red), compared to a nonspecific negative control antibody (Blue).

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP2-02451
    • Availability
      Product Discontinued

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PTP epsilon Antibody (4G2) Summary

Immunogen
Full length human recombinant protein of human PTPRE (NP_006495) produced in HEK293T cell.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
PTPRE
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:2000
  • Flow Cytometry 1:100
  • Immunocytochemistry/Immunofluorescence 1:100

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for PTP epsilon Antibody (4G2)

  • DKFZp313F1310
  • EC 3.1.3.48
  • FLJ57799
  • FLJ58245
  • HPTPE
  • protein tyrosine phosphatase epsilon
  • protein tyrosine phosphatase, receptor type, E
  • protein tyrosine phosphatase, receptor type, epsilon polypeptide
  • Protein-tyrosine phosphatase epsilon
  • PTPE
  • receptor-type tyrosine-protein phosphatase epsilon
  • R-PTP-EPSILON

Background

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Two alternatively spliced transcript variants of this gene have been reported, one of which encodes a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region,and two tandem intracytoplasmic catalytic domains; Another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokines induced SATA signaling, as well as the activation of voltage-gated K+ channels.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for PTP epsilon Antibody (NBP2-02451). (Showing 1 - 1 of 1 FAQ).

  1. Is this antibody specific to the PTPepsilon receptor? Or may it also recognize the PTPalpha?
    • This particular product was made against the full length PTP epsilon peptide. We have not yet tested it for cross reaction against any other phosphatase proteins. Based on an alignment between the epsilon and alpha strains, it looks like there is a probability for cross reaction.

Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for PTP epsilon Antibody (NBP2-02451)

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Diseases for PTP epsilon Antibody (NBP2-02451)

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PTMs for PTP epsilon Antibody (NBP2-02451)

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Bioinformatics

Gene Symbol PTPRE
Entrez