Prothrombin RNAi



Product Details

Reactivity HuSpecies Glossary
Concentration is not relevant for this product. Please see the protocols for proper use of this product.

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Prothrombin RNAi Summary

coagulation factor II (thrombin) (F2), mRNA

Packaging, Storage & Formulations

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Concentration is not relevant for this product. Please see the protocols for proper use of this product.


This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Prothrombin RNAi

  • coagulation factor II (thrombin)
  • Coagulation factor II
  • EC 3.4.21
  • EC
  • prothrombin B-chain
  • prothrombin
  • PT
  • serine protease


Chimera RNA interference (chimera RNAi) is process by which small interfering RNA/DNA chimera triggers the destruction of mRNA for the original gene.  The discovery work, design, and application of chimera RNAi has been pioneered by Professor Kaoru Saigo and Dr. Kumiko Ui-Tei at the University of Tokyo.  Chimera RNAi has many advantages over the conventional siRNAs.  First, it has been demonstrated to have reliable knock-down for over 10,000 human genes.  Because the human genome is composed of an intricate, genetic network, chimera RNAi’s unique design has successfully obviated the off-target effects including microRNA-based influence.  Another advantage of the chimera RNAi technology is its effectiveness at low concentrations (0.5nM to 5nM); only mRNA is destroyed so genomic genes are not affected.  Finally, having both the sense and anti-sense strands consisting RNA/DNA chimera, it offers much greater compound stability for streamlining in vitro and in vivo assays and applications while minimizing interferon induction and other adverse reactions.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. RNAi are guaranteed for 3 months from date of receipt.

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Product General Protocols

View specific protocols for Prothrombin RNAi (H00002147-R01): Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

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Blogs on Prothrombin.

Factor VIII - a key factor in the clotting process
Hemostasis, or blood clotting, follows tissue injury and involves the deployment of essential plasma procoagulants (such as prothrombin, and Factors X, IX, V, and VIII) that trigger the blood coagulation cascade. This cascade leads to the formation...  Read full blog post.

Contact Information

Product PDFs


Gene Symbol F2

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