Protein O-Fucosyltransferase 1/POFUT1 Antibody

Western Blot: Protein O-Fucosyltransferase 1/POFUT1 Antibody [H00023509-D01P] - Analysis of POFUT1 expression in mouse kidney.

Western Blot: Protein O-Fucosyltransferase 1/POFUT1 Antibody [H00023509-D01P] - Analysis of POFUT1 expression in HeLa.

Western Blot: Protein O-Fucosyltransferase 1/POFUT1 Antibody [H00023509-D01P] - Analysis of POFUT1 expression in transfected 293T cell line by POFUT1 polyclonal antibody.Lane 1: POFUT1 transfected lysate(22.30 KDa).Lane 2: Non-transfected lysate.

Product Discontinued

Protein O-Fucosyltransferase 1/POFUT1 Antibody Summary

• Immunogen: POFUT1 (NP_758436.1, 1 a.a. - 194 a.a.) full-length human protein. MGAAAWARPLSVSFLLLLLPLPGMPAGSWDPAGYLLYCPCMGRFGNQADHFLGSLAFAKLLNRTLAVPPWIEYQHHKPPFTNLHVSYQKYFKLEPLQAYHRVISLEDFMEKLAPTHWPPEKRVAYCFEVAAQRSPDKKTCPMKEGNPFGPFWDQFHVSFNKSELFTGISFSASYREQWSQRRENHSCVTLLFPR
• Specificity: POFUT1 - protein O-fucosyltransferase 1,
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: POFUT1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500
• Application Notes: Antibody reactive against recombinant protein with GST tag on ELISA and western blot and also on transfected lysate in western blot. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Protein O-Fucosyltransferase 1/POFUT1 Antibody

• FucT-1
• FUT12
• FUT12EC 2.4.1.221
• GDP-fucose protein O-fucosyltransferase 1
• KIAA0180MGC2482
• o-fucosyltransferase protein
• O-Fuc-T
• O-FucT-1
• O-FUT
• Peptide-O-fucosyltransferase 1
• POFUT1
• Protein OFucosyltransferase 1
• Protein O-Fucosyltransferase 1

Background

This gene encodes a member of the glycosyltransferase O-Fuc family. This enzyme adds O-fucose through an O-glycosidic linkage to conserved serine or threonine residues in the epidermal growth factor-like repeats of a number of cell surface and secreted proteins. O-fucose glycans are involved in ligand-induced receptor signaling. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Protein O-Fucosyltransferase 1/POFUT1 Antibody (H00023509-D01P)(1)

Publication using H00023509-D01P

• Annani-Akollor ME, Wang S, Fan J et al. Downregulated protein O-fucosyl transferase 1 (Pofut1) expression exerts antiproliferative and antiadhesive effects on hepatocytes by inhibiting Notch signalling. Biomed Pharmacother. 2014-07-14 [PMID: 25107841]

Bioinformatics

• Gene Symbol: POFUT1
• Entrez:
  • 23509(Human)
• Uniprot:
  • NP_758436.1(Human)