Protein L Type 1 Recombinant Protein


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Product Details

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Protein L Type 1 Recombinant Protein Summary

A recombinant protein corresponding to Peptostreptococcus Magnus Protein L Type 1

Source: E. coli

Amino Acid Sequence: The amino acid sequence of this product is not available.
E. coli
Details of Functionality
Binding Capacity:Under optimal conditions, 1 mg protein L will bind approximately 5 mg human IgG. Optimal binding of Protein L to antibodies occurs at pH 7.5 over a pH range of 2.5 to 3.0.
Endotoxin Note
<0.1 ng/ug

Packaging, Storage & Formulations

Store at -20C. Avoid freeze-thaw cycles.
No additives.
Reconstitution Instructions
Reconstitute with water to a final concentration of 5.0 mg/ml.


After reconstituted, solution is clear.


Protein L has the unique ability to bind through kappa light chain interactions without interfering with the antibody's antigen-binding site. This gives Protein L the ability to bind a wider range of Ig classes and subclasses than other antibody-binding proteins. Protein L can be used to detect, quantify and purify antibodies and antibody/antigen complexes. 's Recombinant Protein L contains only IgG binding domains. The albumin-binding domain as well as cell wall and cell membrane binding domains have been removed to ensure the maximum specific IgG binding capacity. The 6-His-tag on N-terminus can be used for affinity purification or protein L detection using anti-His-tag antibodies. Protein L binds to all classes of Ig (IgG, IgM, IgA, IgE, and IgD). Protein L will also bind Single Chain Variable Fragments (ScFv) and Fab Fragments. Protein L binds kappa I, III, and IV in human and kappa I on mouse.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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