Proteasome 20S beta 7 Overexpression Lysate (Denatured)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB

Order Details

Proteasome 20S beta 7 Overexpression Lysate (Denatured) Summary

Description
Pasmid: pCMV-PSMB7 full-length
Gene
PSMB7

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Buffer
Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, and 0.01% Bromophenol blue).

Lysate Details for Proteasome 20S beta 7

Type
Overexpression
Protein State
Denatured

Notes

Quality control test: Transient overexpression cell lysate was tested with Anti-PSMB7 antibody by Western Blots.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Proteasome 20S beta 7 Overexpression Lysate (Denatured)

  • EC 3.4.25.1
  • Macropain chain Z
  • Multicatalytic endopeptidase complex chain Z
  • proteasome (prosome, macropain) subunit, beta type, 7
  • proteasome subunit alpha
  • proteasome subunit beta 7
  • proteasome subunit beta type-7
  • Proteasome subunit Z
  • PSMB7
  • Zproteasome catalytic subunit 2

Background

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. Expression of this catalytic subunit is downregulated by gamma interferon and proteolytic processing is required to generate a mature subunit. This subunit is not present in the immunoproteasome and is replaced by catalytic subunit 2i (proteasome beta 10 subunit). [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Lysates are guaranteed for 6 months from date of receipt.

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Publications for Proteasome 20S beta 7 Lysate (H00005695-T01) (0)

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Bioinformatics

Gene Symbol PSMB7