Proteasome 20S alpha 6 Antibody (2A6)

Images

 
Western Blot: Proteasome 20S alpha 6 Antibody (2A6) [NBP2-03838] Analysis of extracts (35ug) from 9 different cell lines by usin g anti-Proteasome 20S alpha 6 monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; ...read more
Flow Cytometry: Proteasome 20S alpha 6 Antibody (2A6) [NBP2-03838] - HEK293T cells transfected with either overexpression plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-Proteasome 20S ...read more
Western Blot: Proteasome 20S alpha 6 Antibody (2A6) [NBP2-03838] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY Proteasome 20S alpha 6 (Right lane) cDNA for 48 hrs and lysed. ...read more

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP2-03838
    • Availability
      Product Discontinued

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Proteasome 20S alpha 6 Antibody (2A6) Summary

Immunogen
Full length human recombinant protein of human PSMA6 (NP_002782) produced in E.coli.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
PSMA6
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1000
  • Flow Cytometry 1:100

Reactivity Notes

Human, Dog, Rat, Monkey, Mouse. Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Proteasome 20S alpha 6 Antibody (2A6)

  • EC 3.4.25.1
  • IOTA
  • Macropain iota chain
  • macropain subunit iota
  • MGC22756
  • MGC2333
  • MGC23846
  • Multicatalytic endopeptidase complex iota chain
  • P27K
  • p27KPROS-27
  • PROS2727 kDa prosomal protein
  • prosomal P27K protein
  • proteasome (prosome, macropain) subunit, alpha type, 6
  • Proteasome iota chain
  • proteasome subunit alpha type-6
  • proteasome subunit iota

Background

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. A pseudogene has been identified on the Y chromosome. [provided by RefSeq].

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PSMA6
Entrez