Recombinant Human Proteasome 20S alpha 2 Protein

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SDS-Page: Proteasome 20S alpha 2 Protein [NBP1-72473]

Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
1 mg/ml

Order Details

Recombinant Human Proteasome 20S alpha 2 Protein Summary

Description
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-234 of Human Proteasome 20S alpha 2

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MAERGYSFSL TTFSPSGKLV QIEYALAAVA GGAPSVGIKA ANGVVLATEK KQKSILYDER SVHKVEPITK HIGLVYSGMG PDYRVLVHRA RKLAQQYYLV YQEPIPTAQL VQRVASVMQE YTQSGGVRPF GVSLLICGWN EGRPYLFQSD PSGAYFAWKA TAMGKNYVNG KTFLEKRYNE DLELEDAIHT AILTLKESFE GQMTEDNIEV GICNEAGFRR LTPTEVKDYL AAIA

Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
PSMA2
Purity
>95% pure by SDS-PAGE

Applications/Dilutions

Theoretical MW
28 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20mM Tris-HCl buffer (pH8.0) containing 30% glycerol, 0.1M NaCl, 1mM DTT, 0.1mM PMSF
Preservative
No Preservative
Concentration
1 mg/ml
Purity
>95% pure by SDS-PAGE

Alternate Names for Recombinant Human Proteasome 20S alpha 2 Protein

  • EC 3.4.25.1
  • HC3PSC2
  • Macropain subunit C3
  • MU
  • Multicatalytic endopeptidase complex subunit C3
  • PMSA2
  • proteasome (prosome, macropain) subunit, alpha type, 2
  • Proteasome component C3
  • proteasome subunit alpha type-2
  • proteasome subunit HC3
  • PSC3

Background

PSMA2, also known as proteasome subunit alpha type-2, is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. PSMA2, belonged to the peptidase T1A family, is a 20S core alpha subunit of proteasome. This protein serves as docking domains for the regulatory particles and exterior gates blocking unregulated access to the interior cavity. Recombinant human PSMA2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol PSMA2