Proprotein Convertase 7/PCSK7 Overexpression Lysate (Denatured)

Images

 
Lane 1: PCSK7 transfected lysate (65.12 KDa) Lane 2: Non-transfected lysate.
PCSK7 transfected lysate.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB

Order Details

Proprotein Convertase 7/PCSK7 Overexpression Lysate (Denatured) Summary

Description
Pasmid: pCMV-PCSK7 full-length
Gene
PCSK7

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Buffer
Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, and 0.01% Bromophenol blue).

Lysate Details for Proprotein Convertase 7/PCSK7

Type
Overexpression
Protein State
Denatured

Notes

Quality control test: Transient overexpression cell lysate was tested with Anti-PCSK7 antibody by Western Blots.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Proprotein Convertase 7/PCSK7 Overexpression Lysate (Denatured)

  • EC 3.4.21
  • EC 3.4.21.-
  • EC 3.4.21.61
  • EC 3.4.21.75
  • EC 3.4.21.93
  • hPC8
  • LPC
  • LPCFLJ23503
  • Lymphoma proprotein convertase
  • PC7FLJ45329
  • PC8prohormone convertase PC7
  • PCSK7
  • Prohormone convertase 7
  • Proprotein Convertase 7
  • Proprotein convertase 8
  • proprotein convertase subtilisin/kexin type 7
  • SPC7
  • SPC7proprotein convertase PC7
  • Subtilisin/kexin-like protease PC7

Background

The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease. It is structurally related to its family members, PACE and PACE4. This protein is concentrated in the trans-Golgi network, associated with the membranes, and is not secreted. It can process proalbumin and is thought to be responsible for the activation of HIV envelope glycoproteins gp160 and gp140. This gene has been implicated in the transcriptional regulation of housekeeping genes. Multiple alternatively spliced transcripts are described for this gene but their full length nature is not yet known. Downstream of this gene's map location at 11q23-q24, nucleotides that match part of this gene's 3' end are duplicated and inverted. A translocation breakpoint associated with lymphoma occurs between this gene and its inverted counterpart. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Lysates are guaranteed for 6 months from date of receipt.

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Bioinformatics

Gene Symbol PCSK7
Entrez