Prokineticin 2 Antibody

Images

 
Immunohistochemistry-Paraffin: Prokineticin 2 Antibody [NBP1-44314] - Analysis of anti-PROKR2 antibody with human thyroid.
Immunohistochemistry-Paraffin: Prokineticin 2 Antibody [NBP1-44314] - Analysis of anti-PROKR2 antibody with human brain, cerebellum.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

Prokineticin 2 Antibody Summary

Immunogen
Synthetic 15 amino acid peptide from N-terminal extracellular domain of human PROKR2.
Specificity
This product is specific for Prokineticin 2. Unless other species reactivities are specified there is no testing data currently available.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PROK2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 1:10-1:500

Reactivity Notes

This antibody is reactive against Human.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Prokineticin 2 Antibody

  • BV8Protein Bv8 homolog
  • KAL4
  • MIT1
  • PK2prokineticin-2
  • prokineticin 2

Background

Prokineticin 2 is known to regulate many different biological functions, including neurogenesis, smooth muscle contractility, angiogenesis and circadian rhythm. In serving the latter role, prokineticin 2 functions as an output molecule from the suprachiasmatic nucleus (SCN) of the hypothalamus, that transmits behavioral rhythms, but may also function locally within the SCN to synchronize output. Prokineticin 2 expression is induced by CLOCK and BMAL1 heterodimers and light, and is inhibited by period genes (PER1, PER2 and PER3) and cryptochrome genes (CRY1 and CRY2). Expression is reported in the SCN and among a few other discrete brain areas, including the islands of Calleja, media l preoptic area of the hypothalamus and the shell of the nucleus accumbens as well as in the testis, prostate and, at lower levels, in the small intestine.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol PROK2