PRKD3/nPKC nu Antibody



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PRKD3/nPKC nu Antibody Summary

Synthetic peptide SANNSPPSAQKSV-C, representing the N-Terminus of the human protein sequence according to NP_005804.
Immunogen affinity purified
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  • Immunohistochemistry 1:200
  • Peptide ELISA 1:32000
Application Notes
Peptide ELISA: antibody detection limit dilution 1:64000. Western Blot: Preliminary experiments gave an approx 47kDa band in human brain lysates at 1ug/ml, this band was successfully blocked by incubation with the immunising peptide. Please note that currently we cannot find an explanation in the literature for the band we observe given the predicted size of approx. 102kDda according to NP_005804. We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported?

Reactivity Notes

Human, Mouse and Rat.

Packaging, Storage & Formulations

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
0.02% Sodium Azide
0.5 mg/ml
Immunogen affinity purified


Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at for more details.

Alternate Names for PRKD3/nPKC nu Antibody

  • EC 2.7.11
  • EC
  • EPK2
  • EPK2PKD3
  • nPKC nu
  • nPKC-nu
  • PKC nu
  • PKC-NU
  • PRKD3
  • Protein kinase C nu type
  • protein kinase C, nu
  • protein kinase D3
  • Protein kinase EPK2
  • protein-serine/threonine kinase
  • serine/threonine-protein kinase D3


Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. This kinase can be activated rapidly by the agonists of G protein-coupled receptors. It resides in both cytoplasm and nucleus, and its nuclear accumulation is found to be dramatically enhanced in response to its activation. This kinase can also be activated after B-cell antigen receptor (BCR) engagement, which requires intact phopholipase C gamma and the involvement of other PKC family members.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Gene Symbol PRKD3