PRELP Overexpression Lysate (Denatured)

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      H00005549-T01
    • Availability
      Product Discontinued

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PRELP Overexpression Lysate (Denatured) Summary

Description
Plasmid: pCMV-PRELP full-length
Gene
PRELP

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Buffer
Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, and 0.01% Bromophenol blue).

Lysate Details for Array

Type
Overexpression
Protein State
Denatured

Notes

Quality control test: Transient overexpression cell lysate was tested with Anti-PRELP antibody by Western Blots.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for PRELP Overexpression Lysate (Denatured)

  • 55 kDa leucine-rich repeat protein of articular cartilage
  • MST161
  • MSTP161
  • PRELP
  • prolargin proteoglycan
  • Prolargin
  • proline arginine-rich end leucine-rich repeat protein
  • proline/arginine-rich end leucine-rich repeat protein
  • Proline-arginine-rich end leucine-rich repeat protein
  • SLRR2A
  • SLRR2AMGC45323

Background

The protein encoded by this gene is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq]. Transcript Variant: This variant (1) represents the longer transcript and encodes the same protein as variant 2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Lysates are guaranteed for 6 months from date of receipt.

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Bioinformatics

Gene Symbol PRELP
Entrez