PP2C gamma/PPM1G Antibody

Images

 
Western Blot: PP2C gamma/PPM1G Antibody [NB110-38869] - Detection of Human and Mouse PPM1G on HeLa whole cell lysate using NB110-38869. PPM1G was also immunoprecipitated by rabbit anti-PPM1G antibody NB110-38867.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NB110-38869
    • Availability
      Product Discontinued

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PP2C gamma/PPM1G Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 500 and the C-terminus (residue 546) of human Protein Phosphatase Magnesium-dependent 1 Gamma using the numbering given in entry NP_817092.1 (GeneID 5496).
Clonality
Polyclonal
Host
Rabbit
Gene
PPM1G
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:2000-1:10000
  • Immunoprecipitation 2-5 ug/mg lysate
Positive Control
HeLa Lysate (NB800-PC1)
PP2C gamma/PPM1G Lysate (NBL1-14662)

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
TBS and 0.1% BSA
Preservative
0.09% Sodium Azide
Concentration
0.2 mg/ml
Purity
Immunogen affinity purified

Alternate Names for PP2C gamma/PPM1G Antibody

  • EC 3.1.3.16
  • MGC1675
  • MGC2870
  • PP2C gamma
  • PP2C, gamma
  • PP2CG
  • PP2CGAMMA
  • PP2C-gamma
  • PPM1C
  • PPM1G
  • PPP2CG
  • Protein phosphatase 1C
  • protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform
  • protein phosphatase 1G
  • protein phosphatase 2, catalytic subunit, gamma isoform
  • protein phosphatase 2C gamma isoform
  • Protein phosphatase 2C isoform gamma
  • Protein phosphatase magnesium-dependent 1 gamma
  • protein phosphatase, Mg2+/Mn2+ dependent, 1G

Background

The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Diseases for PP2C gamma/PPM1G Antibody (NB110-38869)

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Bioinformatics

Gene Symbol PPM1G
Entrez
Uniprot