POR/Cytochrome P450 Reductase Antibody

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Order Details


    • Catalog Number
      NBP1-68853
    • Availability
      Product Discontinued

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POR/Cytochrome P450 Reductase Antibody Summary

Immunogen
Peptide with sequence C-TNPPRTNVLYE corresponding to internal region according to NP_000932.3.
Epitope
C-TNPPRTNVLYE
Clonality
Polyclonal
Host
Goat
Gene
POR
Purity
Immunogen affinity purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Conjugate
Unconjugated
Buffer
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Applications/Dilutions

Dilutions
  • Western Blot 0.1 - 0.3 ug/ml
  • Peptide ELISA Detection limit 1:16000
Application Notes
WB: Approx. 90 kDa band observed in human, mouse and rat liver lysates (calculated MW of 77.0 kDa band according to NP_000932.3).
Publications
Read Publication using NBP1-68853.

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Canine, Bovine, Porcine, Rabbit.

Alternate Names for POR/Cytochrome P450 Reductase Antibody

  • CPR
  • CYPOR
  • CYPORFLJ26468
  • Cytochrome P450 Reductase
  • DKFZp686G04235
  • EC 1.6.2.4
  • NADPH--cytochrome P450 reductase
  • NADPH-dependent cytochrome P450 reductase
  • P450 (cytochrome) oxidoreductase
  • P450R
  • POR/Cytochrome P450 Reductase

Background

This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for POR/Cytochrome P450 Reductase Antibody (NBP1-68853)(1)


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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for POR/Cytochrome P450 Reductase Antibody (NBP1-68853)

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Diseases for POR/Cytochrome P450 Reductase Antibody (NBP1-68853)

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Contact Information

Product PDFs

Bioinformatics

Gene Symbol POR
Entrez
Uniprot

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