Polypeptide GalNac Transferase 4/GALNT4 Overexpression Lysate (Denatured)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB

Order Details

Polypeptide GalNac Transferase 4/GALNT4 Overexpression Lysate (Denatured) Summary

Description
Pasmid: pCMV-GALNT4 full-length
Gene
GALNT4

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Buffer
Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, and 0.01% Bromophenol blue).

Lysate Details for Polypeptide GalNac Transferase 4/GALNT4

Type
Overexpression
Protein State
Denatured

Notes

Quality control test: Transient overexpression cell lysate was tested with Anti-GALNT4 antibody by Western Blots.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Polypeptide GalNac Transferase 4/GALNT4 Overexpression Lysate (Denatured)

  • EC 2.4.1.41
  • FLJ93314
  • GALNACT4
  • GalNAc-T4
  • GALNT4
  • Polypeptide GalNAc transferase 4
  • polypeptide N-acetylgalactosaminyltransferase 4
  • pp-GaNTase 4
  • Protein-UDP acetylgalactosaminyltransferase 4
  • UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 4
  • UDP-N-acetyl-alpha-D-galactosamine:polypeptideN-acetylgalactosaminyltransferase 4 (GalNAc-T4)

Background

This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. In vitro, the encoded protein can complement other GalNAc-Ts in the complete O-glycosylation of the mucin-1 tandem repeat and can O-glycosylate the P-selectin glycoprotein ligand-1 molecule. The coding region of this gene is contained within a single exon. [provided by RefSeq].

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Lysates are guaranteed for 6 months from date of receipt.

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Publications for Polypeptide GalNac Transferase 4/GALNT4 Lysate (H00008693-T01) (0)

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Bioinformatics

Gene Symbol GALNT4
Entrez