POLR3H RNAi

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications RNAi, RNAi SP

Order Details

POLR3H RNAi Summary

Specificity
polymerase (RNA) III (DNA directed) polypeptide H (22.9kD) (POLR3H), transcript variant 4, mRNA
Gene
POLR3H

Applications/Dilutions

Application Notes
This RNAi causes protein knockdown.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for POLR3H RNAi

  • DNA-directed RNA polymerase III subunit 22.9 kDa polypeptide
  • DNA-directed RNA polymerase III subunit H
  • DNA-directed RNA polymerase III subunit RPC8
  • KIAA1665MGC29654
  • MGC111097
  • polymerase (RNA) III (DNA directed) polypeptide H (22.9kD)
  • RNA nucleotidyltransferase (DNA-directed)
  • RNA polymerase III subunit 22.9 kDa subunit
  • RNA polymerase III subunit C8
  • RNA polymerase III subunit RPC8
  • RPC8RPC22.9

Background

Chimera RNA interference (chimera RNAi) is process by which small interfering RNA/DNA chimera triggers the destruction of mRNA for the original gene.  The discovery work, design, and application of chimera RNAi has been pioneered by Professor Kaoru Saigo and Dr. Kumiko Ui-Tei at the University of Tokyo.  Chimera RNAi has many advantages over the conventional siRNAs.  First, it has been demonstrated to have reliable knock-down for over 10,000 human genes.  Because the human genome is composed of an intricate, genetic network, chimera RNAi's unique design has successfully obviated the off-target effects including microRNA-based influence.  Another advantage of the chimera RNAi technology is its effectiveness at low concentrations (0.5nM to 5nM); only mRNA is destroyed so genomic genes are not affected.  Finally, having both the sense and anti-sense strands consisting RNA/DNA chimera, it offers much greater compound stability for streamlining in vitro and in vivo assays and applications while minimizing interferon induction and other adverse reactions.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. RNAi are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol POLR3H