POLR2C RNAi

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications RNAi, RNAi SP

Order Details

POLR2C RNAi Summary

Specificity
polymerase (RNA) II (DNA directed) polypeptide C, 33kDa (POLR2C), transcript variant gamma, mRNA
Gene
POLR2C

Applications/Dilutions

Application Notes
This RNAi causes protein knockdown.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for POLR2C RNAi

  • DNA-directed RNA polymerase II 33 kDa polypeptide
  • DNA-directed RNA polymerase II subunit C
  • DNA-directed RNA polymerase II subunit RPB3
  • hRPB33
  • hsRPB3
  • polymerase (RNA) II (DNA directed) polypeptide C (33kD)
  • polymerase (RNA) II (DNA directed) polypeptide C, 33kDa
  • RNA polymerase II subunit 3
  • RNA polymerase II subunit B3
  • RPB3
  • RPB31
  • RPB33

Background

Chimera RNA interference (chimera RNAi) is process by which small interfering RNA/DNA chimera triggers the destruction of mRNA for the original gene.  The discovery work, design, and application of chimera RNAi has been pioneered by Professor Kaoru Saigo and Dr. Kumiko Ui-Tei at the University of Tokyo.  Chimera RNAi has many advantages over the conventional siRNAs.  First, it has been demonstrated to have reliable knock-down for over 10,000 human genes.  Because the human genome is composed of an intricate, genetic network, chimera RNAi's unique design has successfully obviated the off-target effects including microRNA-based influence.  Another advantage of the chimera RNAi technology is its effectiveness at low concentrations (0.5nM to 5nM); only mRNA is destroyed so genomic genes are not affected.  Finally, having both the sense and anti-sense strands consisting RNA/DNA chimera, it offers much greater compound stability for streamlining in vitro and in vivo assays and applications while minimizing interferon induction and other adverse reactions.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. RNAi are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol POLR2C