PNPO Overexpression Lysate (Denatured)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB

Order Details

PNPO Overexpression Lysate (Denatured) Summary

Description
Pasmid: pCMV-PNPO full-length
Gene
PNPO

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Buffer
Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, and 0.01% Bromophenol blue).

Lysate Details for PNPO

Type
Overexpression
Protein State
Denatured

Notes

Quality control test: Transient overexpression cell lysate was tested with Anti-PNPO antibody by Western Blots.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for PNPO Overexpression Lysate (Denatured)

  • EC 1.4.3.5
  • FLJ10535
  • PDXPO
  • pyridoxal 5'-phosphate synthase
  • pyridoxamine 5'-phosphate oxidase
  • Pyridoxamine-phosphate oxidase
  • pyridoxine 5'-phosphate oxidase
  • pyridoxine-5'-phosphate oxidase

Background

The enzyme encoded by this gene catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine. Mutations in this gene result in pyridoxamine 5'-phosphate oxidase (PNPO) deficiency, a form of neonatal epileptic encephalopathy. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Lysates are guaranteed for 6 months from date of receipt.

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Video Protocols

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Bioinformatics Tool for PNPO Lysate (H00055163-T01)

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Bioinformatics

Gene Symbol PNPO