PLAC1 Antibody

Images

 
Western Blot: PLAC1 Antibody [NBP1-76485] - Human placenta tissue lysate at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
Immunocytochemistry/ Immunofluorescence: PLAC1 Antibody [NBP1-76485] - in Hela cells. Dilution 20 ug/mL.
Immunocytochemistry/ Immunofluorescence: PLAC1 Antibody [NBP1-76485] - in HeLa cells. Dilution 10 ug/mL.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

PLAC1 Antibody Summary

Immunogen
Antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human PLAC1. The immunogen is located within amino acids 130 - 180 of PLAC1. Amino Acid Squence: YEVFSLSQSSQRPN
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PLAC1
Purity
Peptide affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1 ug/ml
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 10-20 ug/ml
Control Peptide
PLAC1 Peptide (NBP1-76485PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Peptide affinity purified

Alternate Names for PLAC1 Antibody

  • cancer/testis antigen 92
  • CT92
  • OOSP2B
  • OOSP2L
  • PLAC1
  • placenta-specific 1
  • placenta-specific protein 1

Background

PLAC1 was initially identified as a protein expressed specifically in the placenta and other cells derived from the trophoblast lineage during embryonic development, but has also been found to be expressed ectopically in a wide range of human malignancies, particularly breast cancers. PLAC1 is a membrane-associated protein that is thought to serve a receptor-like function modulating cell-cell or ligand receptor interactions unique to the maternal-placental interface. Decreased expression of PLAC1 is associated with decreased expression of cyclin D1 and reduced expression of AKT kinase, which, combined with the fact that PLAC1 is expressed on the surface of cancer cells, suggests that PLAC1 may be an effective candidate for immunotherapeutic treatments of cancer.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol PLAC1
Uniprot