PKN1 RNAi

Images

 
Western Blot: PKN1 RNAi [H00005585-R01V] - Analysis of PKN1 over-expressed 293 cell line, cotransfected with PKN1 Validated Chimera RNAi or non-transfected control. Blot probed with H00005585-M01. GAPDH (36.1 kDa) used ...read more
RNAi sequence position: PKN1 RNAi [H00005585-R01V]

Product Details

Summary
Product Discontinued
View other related PKN1 RNAi

Order Details


    • Catalog Number
      H00005585-R01V
    • Availability
      Product Discontinued

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PKN1 RNAi Summary

Specificity
Homo sapiens protein kinase N1, mRNA
Gene
PKN1

Applications/Dilutions

Application Notes
This RNAi causes effective protein knockdown which has been antibody validated.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
DEPC-treated Water

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for PKN1 RNAi

  • DBK
  • EC 2.7.11
  • MGC46204
  • PAK1
  • PAK1Serine-threonine protein kinase N
  • PKN
  • PKN1
  • PKN-ALPHA
  • PKNPKN-ALPHA
  • PRK1
  • PRK1PAK-1
  • PRKCL1
  • PRKCL1protein kinase C-related kinase 1
  • Protease-activated kinase 1
  • Protein kinase C-like 1EC 2.7.11.13
  • Protein kinase C-like PKN
  • protein kinase N1
  • Protein kinase PKN-alpha
  • Protein-kinase C-related kinase 1
  • serine/threonine protein kinase N
  • serine/threonine-protein kinase N1
  • serine-threonine kinase N

Background

Position of the Chimera RNAi. The related RNAi products listed were designed from different accesion number but sharing the same RNAi sequence. Chimera RNA interference (chimera RNAi) is process by which small interfering RNA/DNA chimera triggers the destruction of mRNA for the original gene.  The discovery work, design, and application of chimera RNAi has been pioneered by Professor Kaoru Saigo and Dr. Kumiko Ui-Tei at the University of Tokyo.  Chimera RNAi has many advantages over the conventional siRNAs.  First, it has been demonstrated to have reliable knock-down for over 10,000 human genes.  Because the human genome is composed of an intricate, genetic network, chimera RNAi's unique design has successfully obviated the off-target effects including microRNA-based influence.  Another advantage of the chimera RNAi technology is its effectiveness at low concentrations (0.5nM to 5nM); only mRNA is destroyed so genomic genes are not affected.  Finally, having both the sense and anti-sense strands consisting RNA/DNA chimera, it offers much greater compound stability for streamlining in vitro and in vivo assays and applications while minimizing interferon induction and other adverse reactions.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. RNAi are guaranteed for 3 months from date of receipt.

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Video Protocols

WB Video Protocol

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Diseases for PKN1 RNAi (H00005585-R01V)

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Bioinformatics

Gene Symbol PKN1
Entrez