PKM2 Antibody

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Immunohistochemistry-Paraffin: PKM2 Antibody [NBP1-39660] - Analysis of anti-PKM antibody with human uterus at concentration 5 ug/ml.

Product Details

Summary
Product Discontinued
View other related PKM2 Primary Antibodies

Order Details


    • Catalog Number
      NBP1-39660
    • Availability
      Product Discontinued

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PKM2 Antibody Summary

Immunogen
Pyruvate kinase purified from rabbit muscle.
Specificity
Pyruvate Kinase (Rabbit Muscle).
Clonality
Polyclonal
Host
Goat
Gene
PKM
Purity
IgG purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:2000
  • ELISA 1:4000 - 1:20000
  • Immunohistochemistry-Paraffin 5 ug/ml
  • Immunoprecipitation 1:10-1:500
Publications
Read Publication using NBP1-39660.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20mM Potassium Phosphate (pH 7.2) and 0.15M NaCl
Preservative
0.01% Sodium Azide
Concentration
10 mg/ml
Purity
IgG purified

Alternate Names for PKM2 Antibody

  • CTHBP
  • Cytosolic thyroid hormone-binding protein
  • MGC3932
  • OIP3
  • OIP-3
  • OIP3EC 2.7.1.40
  • Opa-interacting protein 3
  • p58
  • PK, muscle type
  • PK2
  • PK3
  • PK3PKM
  • PKM2
  • Pyruvate kinase 2/3
  • pyruvate kinase isozymes M1/M2
  • Pyruvate kinase muscle isozyme
  • pyruvate kinase, muscle
  • TCB
  • THBP1
  • THBP1p58
  • Thyroid hormone-binding protein 1
  • thyroid hormone-binding protein, cytosolic
  • Tumor M2-PK

Background

The protein encoded by this gene is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. This protein has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for PKM2 Antibody (NBP1-39660)(1)


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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for PKM2 Antibody (NBP1-39660)

Discover related pathways, diseases and genes to PKM2 Antibody (NBP1-39660). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Research Areas for PKM2 Antibody (NBP1-39660)

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Blogs on PKM2.

MAPK3/ERK1 - A signal transduction pathway with roles in development and disease
Mitogen-activated protein kinases (MAPKs) are important signaling proteins needed to transmit and relay extracellular stimuli and to illicit intracellular responses (1). The MAPK family of proteins are serine/threonine kinases that are able to phos...  Read full blog post.

5 Stars for the PKM2 Antibody
Novus' Pyruvate Kinase M2 antibody (cat # NBP1-48308) has received some glowing product reviews and customer feedback lately. One satisfied customer wrote, "The best thing about this antibody is that it works well for immunofluorescence staining of fr...  Read full blog post.

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Bioinformatics

Gene Symbol PKM
Entrez
Uniprot