PKHD1 Antibody [DyLight 488]



Product Details

Product Discontinued
View other related PKHD1 Primary Antibodies

Order Details

    • Catalog Number
    • Availability
      Product Discontinued

    Can't find what you are looking for? Use our Antibody Concierge Service & we will help you locate your antibody!

    Or feel free to contact us for alternative products.

PKHD1 Antibody [DyLight 488] Summary

A synthetic peptide derived from the human PKHD1 protein (within residues 100-200). [UniProt# Q8TCZ9]
Membrane; single-pass type I membrane.
Predicted Species
Mouse (93%). Backed by our 100% Guarantee.
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.


  • Peptide ELISA 1:100-1:2000
Application Notes
This PKHD1 antibody is useful for peptide ELISA.

Reactivity Notes

Human. Immunogen sequence has 93% homology to mouse.

Packaging, Storage & Formulations

Store at 4C in the dark.
50mM Sodium Borate
0.05% Sodium Azide
Immunogen affinity purified


Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at for more details. Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for PKHD1 Antibody [DyLight 488]

  • polycystic kidney and hepatic disease 1 (autosomal recessive)


PKHD1 is a type I membrane protein that undergoes regulated proteolysis. Many proteolytic cleavages occur on the ectodomain whereas at least one cleavage occurs on the cytoplasmic portion of PKHD1. The later generates a C-terminal intracellular fragment that localizes to the nucleus. This proteolysis requires activation of protein kinase C (PKC) and release of intracellular calcium. PKHD1 is expressed in the cilia of the bile duct epithelium and leads to abnormalities in the rubric of the ductal plate malformation. The intracellular C-terminus of PKHD1 interacts with calcium modulating cyclophilin ligand (CAML), a protein implicated in calcium signaling. PKHD1 may participate in the mediation of intracellular calcium in the distal nephron in a manner similar to PKD1 and PKD2. Mutations in the PKHD1 gene result in autosomal recessive polycystic kidney disease (ARPKD), a severe form of polycystic kidney disease characterized by enlarged kidneys and congenital hepatic fibrosis.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

Species: Hu
Applications: ICC/IF, IHC, IHC-P
Species: Hu
Applications: ICC/IF, IHC, IHC-P
Species: Hu
Applications: ICC
Species: Hu, Rt, Ca, Mk, Pm
Applications: WB, Flow, ICC/IF, IHC, IHC-P
Species: Hu
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P
Species: Hu
Applications: WB, Flow, IHC, IP, CyTOF-ready, ELISA(Cap), ELISA(Det), ICC, ELISA(Sta)
Species: Hu, Mu, Rt, Mk
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-P
Species: Hu, Mu
Applications: WB, IP, ICC
Species: Hu, Mu
Applications: WB, Flow, ICC/IF, IHC, IHC-P, PEP-ELISA
Species: Hu
Applications: WB, ELISA, Flow, IHC, CyTOF-ready, ICC
Species: Hu, Rt, Po, Bv, Gt
Applications: WB, ELISA, Flow, ICC/IF, IHC-Fr, IHC-P, IP
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu, Rt
Applications: WB, ICC/IF, IHC, IP, PLA, ICC
Species: Hu
Applications: WB, IHC
Species: Hu
Applications: ICC/IF, IHC, IHC-P

Publications for PKHD1 Antibody (BC110-60477G) (0)

There are no publications for PKHD1 Antibody (BC110-60477G).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for PKHD1 Antibody (BC110-60477G) (0)

There are no reviews for PKHD1 Antibody (BC110-60477G). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

FAQs for PKHD1 Antibody (BC110-60477G) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies


Isotype Controls

Additional PKHD1 Products

Bioinformatics Tool for PKHD1 Antibody (BC110-60477G)

Discover related pathways, diseases and genes to PKHD1 Antibody (BC110-60477G). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for PKHD1 Antibody (BC110-60477G)

Discover more about diseases related to PKHD1 Antibody (BC110-60477G).

Pathways for PKHD1 Antibody (BC110-60477G)

View related products by pathway.

PTMs for PKHD1 Antibody (BC110-60477G)

Learn more about PTMs related to PKHD1 Antibody (BC110-60477G).

Blogs on PKHD1

There are no specific blogs for PKHD1, but you can read our latest blog posts.

Contact Information

Product PDFs


Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.


Review this Product

Be the first to review our PKHD1 Antibody [DyLight 488] and receive a gift card or discount.


Gene Symbol PKHD1