PKC mu Recombinant Protein


There are currently no images for PKC mu Protein (NBP1-99477).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points.

Product Details

0.1 mg/ml

Order Details

PKC mu Recombinant Protein Summary

A recombinant protein corresponding to Human PKC mu

Source: Baculovirus (Sf9 insect cells)

Amino Acid Sequence: The amino acid sequence of this product is not available.
Baculovirus (Sf9 insect cells)
Details of Functionality
680 nmol phosphate incorporated into CREBTIDE substrate peptide per minute per mg protein at 30C for 15 minutes using a final concentration of 50uM ATP (0.83uCi/assay).

Packaging, Storage & Formulations

Store at -80C. Avoid freeze-thaw cycles.
Recombinant proteins in storage buffer (50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol).
0.1 mg/ml

Alternate Names for PKC mu Recombinant Protein

  • EC 2.7.11
  • nPKC-D1
  • nPKC-mu
  • PKCM
  • PKC-MU
  • PKD1
  • PRKD1
  • Protein kinase C mu type
  • protein kinase C, mu
  • Protein kinase D
  • protein kinase D1
  • serine/threonine-protein kinase D1


Protein kinase Cmu (PKCmu) is a novel member of the protein kinase C (PKC) family that differs from the other isoenzymes in structural and enzymatic properties. It is characterized by the presence of a pleckstrin homology (PH) domain and an amino-terminal hydrophobic region and has substrate specificity distinct from other PKC isoforms. PKCmu is a ubiquitous PKC isotype with the highest expression in the thymus, lung and peripheral blood mononuclear cells (1). PKCmu forms a complex in vivo with a phosphatidylinositol 4-kinase and a phosphatidylinositol-4-phosphate 5-kinase. A region of PKCmu between the amino-terminal transmembrane domain and the pleckstrin homology domain is shown to be involved in the association with the lipid kinases (2). PKCmu was also shown to associate with the B cell receptor (BCR) complex and its activity is up-regulated after cross-linking the BCR and CD19 on B cells (3). PKC mu co-precipitates with Syk and phospholipase C-gamma 1/2 (PLC gamma 1/2) and in vitro phosphorylation of fusion proteins showed that both Syk and PLC gamma 1 are potential substrates of PKC mu in vivo. In addition, specific interaction of PKCmu and 14-3-3tau can be shown in the T cell line Jurkat by immunocoprecipitiation and by pulldown assays (4). 14-3-3tau is not a substrate of PKCmu and strongly down-regulates PKCmu kinase activity in vitro. In response to various stimuli, PKC mu activates the mitogen-activated protein kinase (p42/ERK1 MAPK cascade) but does not affect the related c-jun N-terminal kinase or p38 MAPK (5).


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Customers Who Viewed This Item Also Viewed...

Species: Hu
Applications: WB, ELISA, ICC/IF, S-ELISA
Species: Hu, Rt, Ca, Mk, Pm
Applications: WB, Flow, ICC/IF, IHC, IHC-P
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
Species: Hu, Rt, Ca, Mk
Applications: WB, IHC, IHC-P, IP
Species: Hu, Mu
Applications: ICC/IF, PEP-ELISA
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu, Mu
Applications: WB, Simple Western
Species: Hu, Mu, Pm
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu, Mu
Applications: WB, Flow, IHC, ICC
Species: Hu
Applications: WB, IHC, IHC-P, PEP-ELISA
Species: Hu
Applications: WB, IHC
Species: Hu, Mu
Applications: WB, IHC, ICC
Species: Hu
Applications: WB, Simple Western, ICC
Species: Hu, Bv, Ca, Pm
Applications: WB, IHC, IHC-P
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu
Applications: WB, IHC
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IHC-P, S-ELISA
Species: Hu, Mu, Rt
Applications: WB, Simple Western, ICC, ICFlow

Publications for PKC mu Protein (NBP1-99477) (0)

There are no publications for PKC mu Protein (NBP1-99477).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for PKC mu Protein (NBP1-99477) (0)

There are no reviews for PKC mu Protein (NBP1-99477). By submitting a review earn points towards our Rewards Program.
  • 250 points for product review
  • 500 additional points for an image with your product review
  • Double points (500) if you are the first to review this product
  • Double points (1000) if you are the first to review this product with an image

FAQs for PKC mu Protein (NBP1-99477) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Additional PKC mu Recombinant Protein Products

Related Products by Gene

Bioinformatics Tool for PKC mu Protein (NBP1-99477)

Discover related pathways, diseases and genes to PKC mu Protein (NBP1-99477). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for PKC mu Protein (NBP1-99477)

Discover more about diseases related to PKC mu Protein (NBP1-99477).

Pathways for PKC mu Protein (NBP1-99477)

View related products by pathway.

PTMs for PKC mu Protein (NBP1-99477)

Learn more about PTMs related to PKC mu Protein (NBP1-99477).

Research Areas for PKC mu Protein (NBP1-99477)

Find related products by research area.

Blogs on PKC mu

There are no specific blogs for PKC mu, but you can read our latest blog posts.

Contact Information

Product PDFs


Gene Symbol PRKD1

Customer Resources

Novus Review - Submit your review and earn rewards points which can be used for merchandise & discounts.
Risk Free Testing - Test on a species/application not listed above to receive a full credit towards a future purchase.

Novus' Quality Guarantee - Novus guarantees that every product we sell will work in the application and species listed on our website and datasheets.

Submit your question on NBP1-99477 below.
During business hours, we will respond to your email within 24 hours. For any questions submitted on the weekend, a response will be received on Monday.
For immediate assistance during business hours M- F (excluding major holidays), please contact us.
Ask a Scientist - We have a lab full of white coats just waiting for your scientific questions and concerns.

Customers Who Bought This Also Bought

PKC mu Antibody
PKC mu Antibody