PKA R2 Antibody

Images

 
Immunohistochemistry-Paraffin: PKA R2 Antibody [NBP1-50016] - Detection of Human PRKAR2A/PKA-RIIalpha by Immunohistochemistry. Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit ...read more

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-50016
    • Availability
      Product Discontinued

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PKA R2 Antibody Summary

Immunogen
The immunogen for this product maps to a region between residue 50 and 100 of human protein kinase, cAMP-dependent, regulatory, type II, alpha using the numbering given in entry NP_004148.1 (GeneID 5576).
Clonality
Polyclonal
Host
Rabbit
Gene
PRKAR2A
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:100-1:500

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
TBS and 0.1% BSA
Preservative
0.09% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for PKA R2 Antibody

  • protein kinase, cAMP-dependent, regulatory, type II, alpha
  • RII-alpha subunit

Background

PKA (or cAPK) is a cyclic AMP-dependent protein kinase. When activated by the second messenger cAMP, PKA mediates diverse cellular mechanisms, including proliferation, ion transport, regulation of metabolism, and gene transcription (1,2). PKA is comprised of two dimers of two subunits, R (regulatory) and C (catalytic). Two families of R subunits (RI and RII) have been identified, each possessing distinct cAMP binding properties and resulting in different phosphorylation states (2,3).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol PRKAR2A