Western Blot: PIG3 Antibody (3B11) [NBP2-01301] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PIG3 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ...read more
Immunohistochemistry-Paraffin: PIG3 Antibody (3B11) [NBP2-01301] Staining of paraffin-embedded Human Kidney tissue using anti-PIG3 mouse monoclonal antibody.
Immunohistochemistry-Paraffin: PIG3 Antibody (3B11) [NBP2-01301] - Staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-PIG3 mouse monoclonal antibody.
Immunohistochemistry-Paraffin: PIG3 Antibody (3B11) [NBP2-01301] - Staining of paraffin-embedded Human breast tissue using anti-PIG3 mouse monoclonal antibody.
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
0.02% Sodium Azide
Immunogen affinity purified
Alternate Names for PIG3 Antibody (3B11)
p53-induced gene 3 protein
PIG3quinone oxidoreductase homolog
quinone oxidoreductase PIG3
tumor protein p53 inducible protein 3
Tumor protein p53-inducible protein 3
The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. At least two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq].
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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