PI 3-Kinase p110 gamma Antibody Blocking Peptide

Product Discontinued

PI 3-Kinase p110 gamma Antibody Blocking Peptide Summary

• Description: A human PIK3CG antibody blocking peptide.

  Source: Synthetic

  Amino Acid Sequence: C-VLGIKQGEKHSA

• Protein/Peptide Type: Antibody Blocking Peptide
• Gene: PIK3CG
• Purity: >50%, by HPLC

Applications/Dilutions

• Dilutions:
  • Antibody Competition
• Application Notes: This peptide is useful as a blocking peptide for NB100-1097.
  
  For further blocking peptide related protocol, click here.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Lyophilized from a 5pmol/ul solution in 5% (v/v) acetonitrile/H2O and TFA salt.
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: >50%, by HPLC
• Reconstitution Instructions: Reconstitute in 200ul distilled water to obtain a 0.5mg/ml peptide solution.

Alternate Names for PI 3-Kinase p110 gamma Antibody Blocking Peptide

• 1-phosphatidylinositol 3-kinase
• EC 2.7.1
• EC 2.7.1.153
• p110-gamma
• p120-PI3K
• phosphatidylinositol 3 kinase gamma, p110 gamma
• phosphatidylinositol 3-kinase catalytic 110-kD gamma
• phosphatidylinositol 3-kinase, catalytic, gamma polypeptide
• Phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma
• phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
• phosphoinositide-3-kinase gamma catalytic subunit
• phosphoinositide-3-kinase, catalytic, gamma polypeptide
• PI 3Kinase p110 gamma
• PI 3-Kinase p110 gamma
• PI3CG
• PI3K
• PI3K-gamma
• PI3Kgamma
• PI3K-gamma
• PI3-kinase subunit gamma
• PIK3
• PIK3CG
• PtdIns-3-kinase subunit gamma
• PtdIns-3-kinase subunit p110-gamma

Background

PI3-Kinases (PI3-Ks) are a family of lipid kinases that are implicated in signal transduction. PI3-K consists of two subunits; p85 and p10. The p85 subunit localize PI3-K activity to the plasma membrane while the p110 subunit contains the catalytic domain of PI3-K (1-2). Four isoforms of p110 has been found; alpha, beta, gamma, and the delta subunit (3). The gamma isoform is most clostly related to p110 alpha, and beta and has been shown not to interact with p85 in vivo (4). It has been found that in p110-gamma protein expression is lost in primary colorectal adeno-carcinomas and in colon cancer cell lines (5)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PIK3CG