Phospho-SHP-2 (Y542) DuoSet IC ELISA, 2 Plate


A lysate from Jurkat human acute T cell leukemia cells was immunoprecipitated with the Phospho-SHP-2 (Y542) Capture Antibody. Unbound material was removed by washing. The bound material was solubilized in SDS-PAGE more
NIH-3T3 mouse embryonic fibroblast cells were treated with 50 ng/mL of recombinant human PDGF-BB (Catalog # 220-BB) for 20 minutes. The lysates were either quantified with this DuoSet® IC ELISA or immunoblotted more

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Phospho-SHP-2 (Y542) DuoSet IC ELISA, 2 Plate Summary

p Tyr542
Assay Type
Solid Phase Sandwich ELISA
See PDF Datasheet for details
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details


Application Notes
No significant interference observed with available related molecules.
Read Publications using DYC3790-2.

Packaging, Storage & Formulations

Store the unopened product at 2 - 8 °C. Do not use past expiration date.


This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Phospho-SHP-2 (Y542) DuoSet IC ELISA, 2 Plate

  • BPTP3
  • EC
  • MGC14433
  • protein tyrosine phosphatase, non-receptor type 11
  • protein tyrosine phosphatase-2
  • Protein-tyrosine phosphatase 1D
  • Protein-tyrosine phosphatase 2C
  • PTP1D
  • PTP-1D
  • PTP2C
  • PTP-2C
  • PTP2CNS1
  • PTPN11
  • SHP2
  • SHP-2
  • SHPTP2
  • SH-PTP2
  • SH-PTP2Noonan syndrome 1
  • SH-PTP3
  • tyrosine-protein phosphatase non-receptor type 11


The SH2 domain-containing phosphatases, SHP-1 and SHP-2, are well-studied cytosolic tyrosine phosphatases that share many structural and regulatory features. They both have two tandem SH2 domains at the N-terminus, followed by a catalytic domain, and an inhibitory C-terminus. Despite their structural similarity, the enzymes appear to have different physiological roles and exhibit different expression patterns. SHP-1 is highly expressed in hematopoietic tissues, and in general has a negative impact on lymphocyte signaling. In contrast, SHP-2 is widely expressed, and in general promotes signaling pathways that lead to differentiation, cell growth, or migration.

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Publications for SHP-2/PTPN11 (DYC3790-2)(5)

We have publications tested in 2 confirmed species: Human, Rat.

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FAQs for SHP-2/PTPN11 (DYC3790-2). (Showing 1 - 1 of 1 FAQs).

  1. wondering what the difference is between your quantikine and duo set elisas?
    • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

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Gene Symbol PTPN11