Pepsinogen II Antibody (L10CC10)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC, IHC-P
Clone
L10CC10
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
0.1 mg/ml

Order Details

Pepsinogen II Antibody (L10CC10) Summary

Immunogen
The antibody reacts with the Pepsinogen II antigen.
Specificity
The antibody is specific to human pepsinogen II with no cross reactivity to human pepsinogen I. Pepsinogen II is a group of precursor molecules for pepsin. These proteins are secreted into the gastric lumen by the pyloric glands of the gastric antrum and also by the chief and neck cells of the gastric corpus (oxyntic mucosa). Negative immunohistochemical reaction for pepsinogen I (right) but positive reaction for pepsinogen II (left) is a typical sign of the antral mucosa and, in the presence of atrophic gastritis, this staining pattern indicates that the positive glands and cells are metaplastic and pyloric in differentiation (so called pseudopyloric metaplasia). Monoclonal antibody to pepsinogen II is derived from the hybridoma produced by fusion between myeloma cells and Balb/c spleen cells. Pepsinogen II purified from human tissue was used as an immunogen.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
PGA3
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS containing 1.0% w/v BSA
Preservative
0.09% Sodium Azide
Concentration
0.1 mg/ml
Purity
Protein A or G purified

Alternate Names for Pepsinogen II Antibody (L10CC10)

  • pepsinogen 3, group I (pepsinogen A)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Pepsinogen II NBP1-42322

Bioinformatics Tool for Pepsinogen II Antibody (NBP1-42322)

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Diseases for Pepsinogen II Antibody (NBP1-42322)

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Bioinformatics

Gene Symbol PGA3