PEDF R/PNPLA2/ATGL Antibody [DyLight 405]

Images

 
There are currently no images for PEDF R/PNPLA2/ATGL Antibody (NB110-41536V).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 405

PEDF R/PNPLA2/ATGL Antibody [DyLight 405] Summary

Immunogen
A synthetic peptide within the C-terminal region (residues 400-500) of human ATGL. [Accession# NP_005171]
Localization
Cytoplasm, Adiposomes
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PNPLA2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • Immunocytochemistry/Immunofluorescence
Application Notes
This ATGL antibody is useful for Western Blot and Immunocytochemistry/Immunofluorescence. In ICC/IF, cytoplasmic/adiposomal staining was observed in HeLa cells.

Reactivity Notes

Human and mouse.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for PEDF R/PNPLA2/ATGL Antibody [DyLight 405]

  • Adipose triglyceride lipase
  • ATGL
  • ATGL1110001C14Rik
  • Calcium-independent phospholipase A2
  • Desnutrin
  • EC 3.1.1.3
  • FP17548
  • IPLA2-zeta
  • patatin-like phospholipase domain containing 2
  • patatin-like phospholipase domain-containing protein 2
  • patatin-like phospholipase domain-containing protein 2-like
  • PEDF R
  • PEDFR
  • PEDF-R
  • Pigment epithelium-derived factor
  • PNPLA2
  • Transport-secretion protein 2
  • transport-secretion protein 2.2
  • triglyceride hydrolase
  • TTS2
  • TTS2.2
  • TTS-2.2
  • TTS2DKFZp667M109

Background

ATGL (adipose triglyceride lipase) is the rate-limiting lipolytic enzyme which catalyzes initial step of triglyceride (TAG) hydrolysis in adipocytes as well as non-adipocyte lipid droplets. Among adipose lipases (ATGL, hormone-sensitive lipase/HSL and monoacylglycerol lipase), HSL is a diacylglycerol lipase, whereas ATGL prefers TAG substrates. CGI-58 coactivates ATGL's reactions and G0/G1 switch gene 2 exerts supressive effects on ATGL. Localized in lipid droplet and cell membrane as single-pass type II membrane protein, ATGL is mainly expressed in adipose tissue, however, has also been reported in cardiac/skeletal muscles, gastrointestinal tract, normal retina and retinoblastoma. ATGL is inhibited by BEL and is activated by ABHD5 as well as SERPINF1, and is induced during differentiation of primary preadipocytes to adipocytes with expression increasing from fetal to adult in RPE cells. Besides TAG hydrolysis, ATGL has acylglycerol transacylase activity also and can act coordinately with LIPE/HLS within the lipolytic cascade, regulate size of adiposome and implicate in adiposomes degradation. ATGL implicates in energy homeostasis/response to starvation by enhancing TAGs hydrolysis and providing free fatty acids to be oxidized in situations of energy depletion. ATGL genetic variations have been linked with risk of NIDDM and neutral lipid storage disease with myopathy (NLSDM).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

AF1177
Species: Hu, Mu
Applications: WB, Simple Western, IHC
NB110-37253
Species: Hu, Mu, Rt
Applications: WB
NBP2-34260
Species: Hu, Mu, Po, Bv, Rb
Applications: WB, Flow, ICC/IF, IHC-Fr, IHC-P, IP, PAGE
NB110-41576
Species: Hu, Mu, Rt
Applications: WB, Simple Western
NBP1-54155
Species: Hu, Mu
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P
NBP2-22106
Species: Hu, Mu
Applications: WB, IHC, IHC-P
NBP1-81586
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
NB110-40760
Species: Hu, Mu, Rt, Po
Applications: WB, ICC/IF, IHC, IHC-P
NBP2-34294
Species: Hu, Mu, Rt
Applications: WB, Flow, IHC-P
AF7197
Species: Hu, Mu
Applications: WB, IHC, ICC
NB110-40877
Species: Hu, Mu
Applications: WB, Simple Western, ICC/IF, IHC-P
NBP1-86286
Species: Hu
Applications: WB, IHC, IHC-P
NB400-114
Species: Hu, Mu, Rt, Po, Ch, Ha, Pl, Pm
Applications: WB, ICC/IF, IHC, IHC-P, IP
NBP1-00227
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P, PEP-ELISA

Publications for PEDF R/PNPLA2/ATGL Antibody (NB110-41536V) (0)

There are no publications for PEDF R/PNPLA2/ATGL Antibody (NB110-41536V).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for PEDF R/PNPLA2/ATGL Antibody (NB110-41536V) (0)

There are no reviews for PEDF R/PNPLA2/ATGL Antibody (NB110-41536V). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for PEDF R/PNPLA2/ATGL Antibody (NB110-41536V) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional PEDF R/PNPLA2/ATGL Products

Bioinformatics Tool for PEDF R/PNPLA2/ATGL Antibody (NB110-41536V)

Discover related pathways, diseases and genes to PEDF R/PNPLA2/ATGL Antibody (NB110-41536V). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for PEDF R/PNPLA2/ATGL Antibody (NB110-41536V)

Discover more about diseases related to PEDF R/PNPLA2/ATGL Antibody (NB110-41536V).
 

Pathways for PEDF R/PNPLA2/ATGL Antibody (NB110-41536V)

View related products by pathway.

PTMs for PEDF R/PNPLA2/ATGL Antibody (NB110-41536V)

Learn more about PTMs related to PEDF R/PNPLA2/ATGL Antibody (NB110-41536V).
 

Research Areas for PEDF R/PNPLA2/ATGL Antibody (NB110-41536V)

Find related products by research area.

Blogs on PEDF R/PNPLA2/ATGL

There are no specific blogs for PEDF R/PNPLA2/ATGL, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our PEDF R/PNPLA2/ATGL Antibody [DyLight 405] and receive a gift card or discount.

Bioinformatics

Gene Symbol PNPLA2
Entrez