PDZK1 Antibody (1E9)

Images

 
Western Blot: PDZK1 Antibody (1E9) [H00005174-M07] - Analysis of PDZK1 expression in human kidney.
Immunohistochemistry-Paraffin: PDZK1 Antibody (1E9) [H00005174-M07] - Analysis of monoclonal antibody to PDZK1 on formalin-fixed paraffin-embedded human kidney. Antibody concentration 3 ug/ml
Sandwich ELISA: PDZK1 Antibody (1E9) [H00005174-M07] - Detection limit for recombinant GST tagged PDZK1 is approximately 1ng/ml as a capture antibody.

Product Details

Summary
Product Discontinued
View other related PDZK1 Primary Antibodies

Order Details


    • Catalog Number
      H00005174-M07
    • Availability
      Product Discontinued

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PDZK1 Antibody (1E9) Summary

Immunogen
PDZK1 (AAH06496, 1 a.a. ~ 520 a.a) full-length recombinant protein with GST tag.MTSTFNPRECKLSKQEGQNYGFFLRIEKDTEGHLVRVVEKCSPAEKAGLQDGDRVLRINGVFVDKEEHMQVVDLVRKSGNSVTLLVLDGDSYEKAVKTRVDLKELGQSQKEQGLSDNILSPVMNGGVQTWTQPRLCYLVKEGGSYGFSLKTVQGKKGVYMTDITPQGVAMRAGVLADDHLIEVNGENVEDASHEEVVEKVKKSGSRVMFLLVDKETDKRHVEQKIQFKRETASLKLLPHQPRIVEMKKGSNGYGF
Specificity
PDZK1 - PDZ domain containing 1 (1E9)
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
PDZK1
Purity
Ascites
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
Application Notes
This antibody is useful for ELISA, Western Blot
Publications
Read Publication using H00005174-M07.

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
Ascites with PBS (pH 7.4)
Preservative
No Preservative
Purity
Ascites

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for PDZK1 Antibody (1E9)

  • CAP70
  • CFTR-associated protein of 70 kDa
  • CLAMP
  • Na(+)/H(+) exchanger regulatory factor 3
  • Na/Pi cotransporter C-terminal-associated protein 1
  • NaPi-Cap1
  • NHERF3
  • NHERF-3
  • NHERF3PDZD1Na(+)/H(+) exchange regulatory cofactor NHE-RF3
  • PDZ domain containing 1
  • PDZ domain-containing protein 1
  • PDZ-containing kidney protein 1
  • PDZD1
  • PDZK1
  • Sodium-hydrogen exchanger regulatory factor 3

Background

PDZK1 is a scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. It may be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, it may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. It may also play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity. PDZK1 functions to connect SCARB1 with the cellular machineries for intracellular cholesterol transport and/or metabolism and may be involved in the regulation of proximal tubular Na(+)-dependent inorganic phosphate cotransport therefore playing an important role in tubule function.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for PDZK1 Antibody (H00005174-M07)(1)

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Product General Protocols

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol PDZK1
Entrez