PDZK1 Antibody (1E9) Summary
PDZK1 (AAH06496, 1 a.a. ~ 520 a.a) full-length recombinant protein with GST tag.MTSTFNPRECKLSKQEGQNYGFFLRIEKDTEGHLVRVVEKCSPAEKAGLQDGDRVLRINGVFVDKEEHMQVVDLVRKSGNSVTLLVLDGDSYEKAVKTRVDLKELGQSQKEQGLSDNILSPVMNGGVQTWTQPRLCYLVKEGGSYGFSLKTVQGKKGVYMTDITPQGVAMRAGVLADDHLIEVNGENVEDASHEEVVEKVKKSGSRVMFLLVDKETDKRHVEQKIQFKRETASLKLLPHQPRIVEMKKGSNGYGF
PDZK1 - PDZ domain containing 1 (1E9)
Test in a species/application not listed above to receive a full credit towards a future purchase.
- Western Blot 1:100-1:2000
- ELISA 1:100-1:2000
- Immunohistochemistry 1:10-1:500
- Immunohistochemistry-Paraffin 1:10-1:500
This antibody is useful for ELISA, Western Blot
Packaging, Storage & Formulations
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Ascites with PBS (pH 7.4)
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for PDZK1 Antibody (1E9)
- CFTR-associated protein of 70 kDa
- Na(+)/H(+) exchanger regulatory factor 3
- Na/Pi cotransporter C-terminal-associated protein 1
- NHERF3PDZD1Na(+)/H(+) exchange regulatory cofactor NHE-RF3
- PDZ domain containing 1
- PDZ domain-containing protein 1
- PDZ-containing kidney protein 1
- Sodium-hydrogen exchanger regulatory factor 3
PDZK1 is a scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. It may be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, it may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. It may also play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity. PDZK1 functions to connect SCARB1 with the cellular machineries for intracellular cholesterol transport and/or metabolism and may be involved in the regulation of proximal tubular Na(+)-dependent inorganic phosphate cotransport therefore playing an important role in tubule function.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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