PDX-1/IPF1 Antibody (5D5)

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Western Blot: PDX1 Antibody (5D5) [NBP1-47911] Analysis of extracts (35ug) from 9 different cell lines by using anti-PDX1 monoclonal antibody.
Western Blot: PDX1 Antibody (5D5) [NBP1-47911] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PDX1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ...read more

Product Details

Summary
Product Discontinued
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    • Catalog Number
      NBP1-47911
    • Availability
      Product Discontinued

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PDX-1/IPF1 Antibody (5D5) Summary

Immunogen
Recombinant protein expressed in E.coli corresponding to amino acids 1-283 of human Pdx1
Specificity
This antibody is specific for Homo sapiens pancreatic and duodenal homeobox 1 (PDX1).
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
PDX1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:5000-10000

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for PDX-1/IPF1 Antibody (5D5)

  • Glucose-sensitive factor
  • IDX1
  • IDX-1GSF
  • Insulin promoter factor 1
  • insulin promoter factor 1, homeodomain transcription factor
  • Insulin upstream factor 1
  • IPF1
  • IPF1pancreas/duodenum homeobox protein 1
  • Islet/duodenum homeobox-1
  • MODY4IUF1
  • pancreatic and duodenal homeobox 1
  • pancreatic-duodenal homeobox factor 1
  • PDX-1
  • PDX-1IPF-1
  • somatostatin transcription factor 1
  • Somatostatin-transactivating factor 1
  • STF-1IUF-1

Background

Pdx1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. It is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in PDX1 gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Diseases for PDX-1/IPF1 Antibody (NBP1-47911)

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Bioinformatics

Gene Symbol PDX1
Entrez