PDGF R beta Antibody

Images

 
Western Blot: PDGF R beta Antibody [NB100-82136] - Analysis of extracts from HepG2 cells using PDGF R beta (Ab-751) antibody
Western Blot: PDGF R beta Antibody [NB100-82136] - Analysis of extract from 293 cells, using PDGF R beta (Ab-751) antibody.

Product Details

Summary
Product Discontinued
View other related PDGF R beta Primary Antibodies

Order Details


    • Catalog Number
      NB100-82136
    • Availability
      Product Discontinued

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PDGF R beta Antibody Summary

Immunogen
The antiserum was produced against synthesized non-phosphopeptide derived from human PDGF Receptor beta around aa. 751 (V-D-Y-V-P).
Specificity
PDGF Receptor beta (specific to a.a. 751) detects endogenous levels of total PDGF Receptor beta protein.
Clonality
Polyclonal
Host
Rabbit
Gene
PDGFRB
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000
Theoretical MW
190 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Positive Control
PDGF R beta Lysate (NBL1-14239)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, and 50% glycerol.
Preservative
0.02% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for PDGF R beta Antibody

  • beta-type platelet-derived growth factor receptor
  • CD140 antigen-like family member B
  • CD140b antigen
  • CD140b
  • EC 2.7.10
  • EC 2.7.10.1
  • JTK12
  • PDGF R beta
  • PDGFR
  • PDGFR1
  • PDGFRB
  • PDGF-R-beta
  • platelet-derived growth factor receptor, beta polypeptide

Background

Platelet-derived growth factor receptors exhibit tyrosine-protein kinase activity and have been implicated in the control of cell proliferation, survival and migration. PDGF receptors, PDGFR-alpha and PDGFR-beta, have 5 extracellular immunoglobulin-like domains and an intracellular tyrosine kinase domain. Upon binding a PDGF, the receptors form homo-and heterodimers. Dimerization of the receptors results in phosphorylation in the complex. More than 10 different SH2-domain-containing molecules have been shown to bind to different autophosphorylation sites in the PDGF-alpha and beta receptors. PDGF alpha receptors are expressed in oligodendrocyte progenitor cells and PDGF beta receptors are expressed on neurons.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol PDGFRB
Entrez
Uniprot