Recombinant Human PDGF-B Protein

Images

 
ELISA: PDGFB Protein [NBP1-43180] - Standard curve of Human PDGF-BB Recombinant Protein.
ELISA: PDGFB Protein [NBP1-43180] - Proliferation of Balb/c-3T3 cells in response to Human PDGF-BB Recombinant Protein

Product Details

Summary
Product Discontinued
View other related PDGF-B Peptides and Proteins

Order Details


    • Catalog Number
      NBP1-43180
    • Availability
      Product Discontinued

    Can't find what you are looking for? Use our Antibody Concierge Service & we will help you locate your antibody!

    Or feel free to contact us for alternative products.

Recombinant Human PDGF-B Protein Summary

Description
A partial recombinant protein with a His tag corresponding to amino acids Ser67 - Thr175 of PDGFB.
Preparation
Method
E. coli.
Protein/Peptide Type
Partial Recombinant Protein
Gene
PDGFB
Endotoxin Note
Less than 0.01 ng/ug cytokine as determined by the LAL assay.

Applications/Dilutions

Dilutions
  • Functional < 30 ng/ml
Application Notes
The ED50 of this protein, as measured by Balb/c-3T3 proliferation, is less than or equal to 30 ng/mL. This corresponds to a specific activity of greater than or equal to 3.3 x 10e4 Units/mg
Theoretical MW
24.9 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

This protein was made to the human sequence.

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Buffer
Phosphate buffered saline, pH 7.2, 150 mM NaCl, with 1.0% BSA. 0.22 um filtered.For best recovery, quick-spin vial prior to opening. Use in a sterile environment
Preservative
0.09% Sodium Azide
Concentration
0.1 mg/ml

Alternate Names for Recombinant Human PDGF-B Protein

  • B chain
  • Becaplermin
  • FLJ12858
  • PDGF subunit B
  • PDGF2
  • PDGF-2
  • PDGFB
  • PDGF-B
  • platelet-derived growth factor 2
  • platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis)oncogene homolog)
  • Platelet-derived growth factor beta polypeptide
  • platelet-derived growth factor subunit B
  • platelet-derived growth factor, B chain
  • Platelet-derived growth factor, beta polypeptide (oncogene SIS)
  • Proto-oncogene c-Sis
  • SSV

Background

PDGF-BB is a member of the platelet-derived growth factor family, a group of proteins that are released by platelets upon activation. The PDGF proteins are dimers of two of four peptide chains designated A, B, C, and D. PDGF-BB is formed by two B-chains, while PDGF-AB is one B chain and one A-chain forming the only heterodimer in the family. PDGF-BB is unique among the family in that it can bind to and activate all three forms of the PDGF receptor. It induces the proliferation, migration, and survival of fibroblasts, endothelial cells, epithelial cells, and smooth muscle cells. PDGF-BB is important for angiogenesis and smooth muscle formation during embryonic development, and plays a role in wound healing and regeneration in adults. High levels of PDGF-BB are often detected in malignant tumors, and it is believed to facilitate tumor metastasis and vascularization.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Customers Who Viewed This Item Also Viewed...

221-AA
Species: Hu
NB600-408
Species: Hu, Mu, Rt, Po, Bv, Rb
Applications: WB, ELISA, ICC/IF, IHC, IHC-Fr, IHC-P, IP
NB110-60980
Species: Hu
Applications: WB, Flow, IHC, IHC-P, CyTOF-ready
AF385
Species: Hu
Applications: WB, Flow, IHC, CyTOF-ready, Neut
NB600-335
Species: Hu, Mu, Ec, NA
Applications: WB, ELISA, ICC/IF, IHC-Fr, IP
NBP2-50037
Species: Hu, Mu, Rt, Po, Bv, Eq
Applications: WB, ICC/IF
AF231
Species: Hu
Applications: WB, Flow, IHC, IP, CyTOF-ready, ELISA(Cap), ELISA(Det), ICC, ELISA(Sta)
NBP2-14357
Species: Hu
Applications: IHC, IHC-P
AF4928
Species: Hu
Applications: WB, Flow, CyTOF-ready
NB600-1071
Species: Mu, Rt
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP
AF1356
Species: Hu, Mu
Applications: WB, Simple Western, Flow, IHC, CyTOF-ready
NB200-106
Species: Mu
Applications: WB, ELISA, ICC/IF, IHC, IHC-Fr, IHC-P
NBP1-43180
Species: Hu
Applications: Func, IA

Publications for PDGF-B Protein (NBP1-43180) (0)

There are no publications for PDGF-B Protein (NBP1-43180).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for PDGF-B Protein (NBP1-43180) (0)

There are no reviews for PDGF-B Protein (NBP1-43180). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

FAQs for PDGF-B Protein (NBP1-43180) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Additional PDGF-B Products

Bioinformatics Tool for PDGF-B Protein (NBP1-43180)

Discover related pathways, diseases and genes to PDGF-B Protein (NBP1-43180). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for PDGF-B Protein (NBP1-43180)

Discover more about diseases related to PDGF-B Protein (NBP1-43180).
 

Pathways for PDGF-B Protein (NBP1-43180)

View related products by pathway.

PTMs for PDGF-B Protein (NBP1-43180)

Learn more about PTMs related to PDGF-B Protein (NBP1-43180).
 

Research Areas for PDGF-B Protein (NBP1-43180)

Find related products by research area.

Blogs on PDGF-B

There are no specific blogs for PDGF-B, but you can read our latest blog posts.

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our Recombinant Human PDGF-B Protein and receive a gift card or discount.

Bioinformatics

Gene Symbol PDGFB
Entrez