PDE8A Overexpression Lysate (Denatured)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB

Order Details

PDE8A Overexpression Lysate (Denatured) Summary

Description
Pasmid: pCMV-PDE8A full-length
Gene
PDE8A

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Buffer
Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, and 0.01% Bromophenol blue).

Lysate Details for PDE8A

Type
Overexpression
Protein State
Denatured

Notes

Quality control test: Transient overexpression cell lysate was tested with Anti-PDE8A antibody by Western Blots.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for PDE8A Overexpression Lysate (Denatured)

  • cAMP-specific cyclic nucleotide phosphodiesterase 8A
  • EC 3.1.4.17
  • FLJ16150
  • high affinity cAMP-specific and IBMX-insensitive 3'-5'-cyclic phosphodiesterase8A
  • high-affinity cAMP-specific and IBMX-insensitive 3'-5'-cyclic phosphodiesterase8A
  • HsT19550
  • phosphodiesterase 8A

Background

Phosphodiesterases (PDEs) regulate the intracellular levels of cAMP and cGMP. These cyclic nucleotides play an important role as second messengers in multiple physiologic processes, including regulation of vascular resistance, cardiac output, visceral motility, immune response, inflammation, neuroplasticity, vision, and reproduction. PDEs comprise a large superfamily of enzymes divided into 10 families. Different PDEs can be distinguished by their structure, tissue expression, localization, substrate specificity, regulation, and sensitivity to PDE inhibitors. Diversity in structure and specificity of function make PDEs promising targets for the pharmacotherapy of diseases modulated by cyclic nucleotide signaling (Hetman et al., MIM 2000). See MIM 171885.[supplied by OMIM].

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Lysates are guaranteed for 6 months from date of receipt.

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Publications for PDE8A Lysate (H00005151-T01) (0)

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Product General Protocols

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Video Protocols

WB Video Protocol

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Bioinformatics

Gene Symbol PDE8A