PDE4B Antibody (2B6)

Images

 
Western Blot: PDE4B Antibody (2B6) [NBP2-01149] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PDE4B (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates ...read more
Immunocytochemistry/ Immunofluorescence: PDE4B Antibody (2B6) [NBP2-01149] Staining of COS7 cells transiently transfected by pCMV6-ENTRY PDE4B.
Immunohistochemistry-Paraffin: PDE4B Antibody (2B6) [NBP2-01149] - Staining of paraffin-embedded Human pancreas tissue using anti-PDE4B mouse monoclonal antibody.
Flow Cytometry: PDE4B Antibody (2B6) [NBP2-01149] - HEK293T cells transfected with either overexpression plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-PDE4B antibody, and then analyzed ...read more

Product Details

Summary
Product Discontinued
View other related PDE4B Primary Antibodies

Order Details


    • Catalog Number
      NBP2-01149
    • Availability
      Product Discontinued

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PDE4B Antibody (2B6) Summary

Immunogen
Full length human recombinant protein of human PDE4B(NP_002591) produced in HEK293T cell
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
PDE4B
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1:2000
  • Flow Cytometry 1:100
  • Immunocytochemistry/Immunofluorescence 1:100
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:150

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for PDE4B Antibody (2B6)

  • cAMP-specific (phosphodiesterase E4 dunce homolog
  • cAMP-specific 3'-5'-cyclic phosphodiesterase 4B
  • cAMP-specific phosphodiesterase-4 B isoform
  • DKFZp686F2182
  • Drosophila)
  • dunce-like phosphodiesterase E4
  • EC 3.1.4
  • EC 3.1.4.17
  • MGC126529
  • PDE32
  • PDEIVB
  • phosphodiesterase 4B, cAMP-specific (dunce (Drosophila)-homologphosphodiesterase E4)
  • phosphodiesterase 4B, cAMP-specific (dunce
  • phosphodiesterase 4B, cAMP-specific
  • phosphodiesterase E4 dunce homolog

Background

This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq].

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Bioinformatics

Gene Symbol PDE4B
Entrez