PD-L2/B7-DC/PDCD1LG2 Antibody (122) [Biotin]


Flow Cytometry: PD-L2/B7-DC/PDCD1LG2 Antibody (122) [Biotin] [NBP1-43468] - Staining of in vitro BM-derived dendritic cells from BALB/c with 0.06 ug of Rat IgG2a Isotype Control Biotin (open histogram) or 0.06 ug of ...read more

Product Details

Reactivity MuSpecies Glossary
Applications Flow
0.5 mg/ml

Order Details

PD-L2/B7-DC/PDCD1LG2 Antibody (122) [Biotin] Summary

The immunogen for this antibody was B7DC.
IgG2a Kappa
Protein A or G purified
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Packaging, Storage & Formulations

Store at 4C. Do not freeze.
Biotin (A=N/A, E=N/A)
Aqueous buffer, may contain carrier protein/stabilizer (proprietary)
0.09% Sodium Azide
0.5 mg/ml
Protein A or G purified


Application Notes
The 122 antibody has been tested by flow cytometric analysis of mouse dendritic cell suspensions and mouse B7-DC transfected cells. This can be used at less than or equal to 0.5 ug per test. Cell number should be determined empirically but can range from 10^5to 10^8cells/test.
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Alternate Names for PD-L2/B7-DC/PDCD1LG2 Antibody (122) [Biotin]

  • B7-DC
  • bA574F11.2
  • Btdc
  • Butyrophilin B7-DC
  • Butyrophilin-like Protein
  • CD273 antigen
  • CD273
  • CD273PD-1 ligand 2
  • MGC142240
  • PD-1-ligand 2
  • PDCD1L2MGC142238
  • PDCD1LG2
  • PDL2
  • PDL2B7DC
  • PD-L2PDCD1 ligand 2
  • programmed cell death 1 ligand 2
  • Programmed death ligand 2


The 122 monoclonal antibody reacts with mouse B7-DC, also known as PD-L2. B7-DC, a recently identified member of the B7 family, has a predicted molecular weight of approximately 25 kDa and belongs to the Ig superfamily. The mouse B7-DC has a short cytoplasmic tail (4aa). B7-DC is primarily expressed by subpopulations of dendritic cells and monocytes/macrophages in the mouse. Although B7-DC has structural and sequence similarities to the B7 family, it does not bind CD28/CTLA-4, rather it is a ligand for PD-1. The interactions between PD-1 and B7-DC/PD-L2 have been reported to be involved in costimulation or suppression of T cell proliferation depending on state of cellular activation. 122 has been demonstrated to block binding of TY25, another mAb specific for mouse B7-DC.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies


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Gene Symbol PDCD1LG2

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