PD-1 Antibody

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Immunohistochemistry-Paraffin: PD1 Antibody [NBP1-49772] - Human Lymph Node

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-49772
    • Availability
      Product Discontinued

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PD-1 Antibody Summary

Immunogen
A synthetic peptide derived from internal region of human PD-1/CD279 protein
Clonality
Polyclonal
Host
Rabbit
Gene
PDCD1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
Application Notes
This product is useful for Immunohistochemistry Paraffin. Antigen retrieval can be performed using a Citrate process. Immunocytochemistry/Immunofluorescence was reported in scientific literature.
Publications
Read Publication using
NBP1-49772 in the following applications:

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
7.0 ml prediluted antibody with 10mM PBS (pH 7.4) and 1.0% BSA
Preservative
0.1% Sodium Azide
Purity
Immunogen affinity purified

Notes

For a positive control use Colon and breast.

Alternate Names for PD-1 Antibody

  • CD279 antigen
  • CD279
  • hPD-1
  • PD-1
  • PD1hPD-l
  • PDCD1
  • programmed cell death 1
  • programmed cell death protein 1
  • Protein PD-1
  • SLEB2

Background

CD279 is a 50-55 kD immunoglobulin superfamily member, also known as programmed death-1 (PD-1). PD-1 is expressed on a subset of CD4-CD8- thymocytes, and on activated T and B cells. PD-1 is thought to be involved in lymphocyte clonal selection and peripheral tolerance. The PD-1 ligands, PD-L1 (also known as B7-H1) and PD-L2 (B7-DC), are members of the B7 immunoglobulin superfamily. The RMP1-14 antibody has been reported to block the binding of PD-1 to its ligands (B7-H1 and B7-DC) and to inhibit T cell proliferation and cytokine production costimulated by macrophages (but not by dendritic cells and B cells).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for PD-1 Antibody (NBP1-49772)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: ICC/IF, IHC.


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ICC/IF
(1)
IHC
(1)
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Filter By Species
Human
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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for PD-1 Antibody (NBP1-49772)

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Blogs on PD-1.

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Here at Bio-Techne we always look forward to the annual announcements of winners of the highly coveted Nobel Prize – the greatest award in science. How can you go about predicting which scientists might be in line for a life-changing phone-call fro...  Read full blog post.

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Bioinformatics

Gene Symbol PDCD1
Entrez