Park7/DJ-1 Antibody

Images

 
Immunohistochemistry: Park7/DJ-1 Antibody [NBP1-00782] - Analyzes of DEF-3 (K989) antibody in paraffin-embedded human brain tissue.

Product Details

Summary
Product Discontinued
View other related Park7/DJ-1 Primary Antibodies

Order Details


    • Catalog Number
      NBP1-00782
    • Availability
      Product Discontinued

    Can't find what you are looking for? Use our Antibody Concierge Service & we will help you locate your antibody!

    Or feel free to contact us for alternative products.

Park7/DJ-1 Antibody Summary

Immunogen
Synthetic peptide, corresponding to amino acids 50-97 of Human PARK7 / DJ-1.
Clonality
Polyclonal
Host
Rabbit
Gene
PARK7
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:50-1:200
Application Notes
Western blot (WB) analysis of Park7(DJ-1) (A87) pAb in extracts from HT-29 cells.
Theoretical MW
20 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

This antibody is reactive against Human, Mouse, Rat

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2)
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Park7/DJ-1 Antibody

  • DJ1
  • DJ-1
  • DJ1FLJ34360
  • EC 3.4
  • FLJ27376
  • FLJ92274
  • Oncogene DJ1
  • Park7
  • Parkinson disease (autosomal recessive, early onset) 7
  • Parkinson disease protein 7
  • protein DJ-1

Background

The DJ-1 gene encodes a highly-conserved protein which is implicated in a number of cell processes. DJ-1 was first identified as a novel oncogene that transformed mouse NIH/3T3 cells in cooperation with activated Ras. Additionally, DJ-1 was cloned in rat as SP22 or CAP-1, and found to be an infertilityrelated sperm protein whose expression is reduced in sperm treated with toxicants. DJ-1 also positively regulates the androgen receptor (AR) by forming a complex with PIASxalpha, a negative regulator of AR. The gene encoding human DJ-1 maps to chromosome 1p36.33-p36.12, a region identified as a hot spot of chromosome abnormalities in several tumor cells. Subsequently, mutations in the DJ-1 gene have been implicated in Parkinson's disease, and loss of DJ-1 function leads to neurodegeneration. DJ-1 is a ubiquitously expressed protein that is induced in response to growth stimuli and translocates from the cytoplasm to the nucleus during the S phase of the cell cycle.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP1-26380
Species: Hu, Mu
Applications: WB, Flow, ICC/IF, IHC, IHC-Fr, IHC-P
BC100-494
Species: Hu, Mu, Rt, Dr
Applications: WB, ICC/IF, IHC, IHC-P, IP, PEP-ELISA
NB300-268
Species: Hu, Mu, Bv, Ce
Applications: WB, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP
NB600-1160
Species: Hu, Mu, Rt, Po, Bv
Applications: WB, Simple Western, ELISA, ICC/IF, IHC, IHC-Fr, IHC-P
H00005071-M01
Species: Hu, Rt
Applications: WB, ELISA, ICC/IF
NBP1-32822
Species: Hu, Mu, Rt
Applications: WB, ChIP, ICC/IF, IHC, IHC-P, IP
NB110-41486
Species: Hu, Mu
Applications: WB, Simple Western, IHC
NB100-56749
Species: Hu, Mu
Applications: WB, IHC, IHC-P
NB300-109
Species: Hu, Mu, Rt, Dr, I, Ma
Applications: WB, Simple Western, ICC/IF, IHC, IHC-Fr, IHC-P, IHC-FrFl
NBP2-25162
Species: Hu, Mu, Rt
Applications: WB, ICC/IF
AF847
Species: Hu, Mu, Rt
Applications: WB, Simple Western, IHC, CyTOF-ready, ICFlow
NB200-103
Species: Hu, Mu, Rt, Ye, Xp(-)
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, CyTOF-ready, Flow-IC
AF6008
Species: Hu, Mu, Rt
Applications: WB
NBP2-24915
Species: Hu, Mu, Rt, Bv
Applications: WB, IHC-P
NB100-56077
Species: Hu
Applications: WB, IHC, IHC-P, IP
H00002551-M03
Species: Hu
Applications: WB, ELISA, ICC/IF, IP
NB100-56603
Species: Hu, Pm
Applications: WB, IHC, IHC-P
NBP1-00782
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P

Publications for Park7/DJ-1 Antibody (NBP1-00782) (0)

There are no publications for Park7/DJ-1 Antibody (NBP1-00782).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for Park7/DJ-1 Antibody (NBP1-00782) (0)

There are no reviews for Park7/DJ-1 Antibody (NBP1-00782). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for Park7/DJ-1 Antibody (NBP1-00782) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional Park7/DJ-1 Products

Bioinformatics Tool for Park7/DJ-1 Antibody (NBP1-00782)

Discover related pathways, diseases and genes to Park7/DJ-1 Antibody (NBP1-00782). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for Park7/DJ-1 Antibody (NBP1-00782)

Discover more about diseases related to Park7/DJ-1 Antibody (NBP1-00782).
 

Pathways for Park7/DJ-1 Antibody (NBP1-00782)

View related products by pathway.

PTMs for Park7/DJ-1 Antibody (NBP1-00782)

Learn more about PTMs related to Park7/DJ-1 Antibody (NBP1-00782).
 

Research Areas for Park7/DJ-1 Antibody (NBP1-00782)

Find related products by research area.

Blogs on Park7/DJ-1.

Park7/DJ-1: A Reliable Biomarker for Parkinson's Disease?
The product of the Parkinson's disease 7 (Park7/DJ-1) gene belongs to the peptidase C56 family of proteins and appears to have two transcriptional variants. It is a positive regulator of androgen receptor-dependent transcription, and some evidence sug...  Read full blog post.

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our Park7/DJ-1 Antibody and receive a gift card or discount.

Bioinformatics

Gene Symbol PARK7
Entrez