pan MAGUK Antibody

Images

 
Western Blot: pan MAGUK Antibody [NBP1-68836] - Staining of Rat Brain lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Product Details

Summary
Reactivity RtSpecies Glossary
Applications WB, PEP-ELISA
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated

Order Details

pan MAGUK Antibody Summary

Immunogen
Peptide with sequence C-EEQARKAFDRATK corresponding to internal region (near C-Terminus) according to NP_001122299.1.
Epitope
C-EEQARKAFDRATK
Marker
post-Synaptic Marker
Specificity
This antibody is expected to recognize both reported isoforms (NP_001356.1; NP_001122299.1)
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
DLG4
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 0.3 - 1 ug/ml
  • Peptide ELISA Detection limit 1:64000
Application Notes
WB: Approx. 110 kDa band observed in rat brain lysates is reported in scientific literature (PMID: 19679819).
Publications
Read Publications using NBP1-68836.

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Human, Mouse, Canine, Bovine.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for pan MAGUK Antibody

  • discs, large homolog 4 (Drosophila)
  • disks large homolog 4
  • FLJ97752
  • FLJ98574
  • Postsynaptic density protein 95
  • post-synaptic density protein 95
  • PSD-95
  • PSD95SAP90SAP-90discs large homolog 4
  • Synapse-associated protein 90
  • Tax interaction protein 15

Background

Membrane associated guanylate kinases (MAGUKs) form a family of scaffolding proteins, which are often associated with cellular junctions. Their capacity to serve a platforms for organizing larger protein assemblies results from the presence of several protein-protein interaction domains. PDZ-domain containing proteins of the MAGUK family target, anchor and cluster receptors and channels to subcellular sites.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for pan MAGUK Antibody (NBP1-68836)(2)

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol DLG4
Entrez
Uniprot