PAK2 Antibody

Images

 
Western Blot: PAK2 Antibody [NB100-60457] - Detection of Human PAK2 on HeLa whole cell lysate using NB100-60457. PAK2 was also immunoprecipitated by rabbit anti-PAK2 antibodies NB100-60456 and, another PAK2.

Product Details

Summary
Product Discontinued
View other related PAK2 Primary Antibodies

Order Details


    • Catalog Number
      NB100-60457
    • Availability
      Product Discontinued

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PAK2 Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 125 and 175 of human p21 (CDKN1A)-activated kinase 2 using the numbering given in entry NP_002568.2 (GeneID 5062).
Clonality
Polyclonal
Host
Rabbit
Gene
PAK2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:2000-1:10000
  • Immunoprecipitation 1:10-1:500

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
TBS and 0.1% BSA
Preservative
0.09% Sodium Azide
Concentration
0.2 mg/ml
Purity
Immunogen affinity purified

Alternate Names for PAK2 Antibody

  • EC 2.7.11
  • gamma-PAK
  • p21 (CDKN1A)-activated kinase 2
  • p21 protein (Cdc42/Rac)-activated kinase 2
  • p21-activated kinase 2
  • p58
  • PAK2
  • PAK-2
  • PAK65
  • PAK65EC 2.7.11.1
  • PAKgamma
  • S6/H4 Kinase
  • serine/threonine-protein kinase PAK 2

Background

PAK2 (p21-activated kinase 2) is part of the family of PAK serine/threonine p21-activating protein kinases involved in cell survival, migration, and invasion. The PAK family of proteins mediates signals from extracellular stimuli to the cytoplasm and nucleus via its association with the small GTP-binding proteins Cdc42 and Rac. PAK2 has been shown to play a specific role in apoptosis and cytoskeletal dynamics. During caspase-mediated apoptosis, PAK2 is cleaved and the C-terminal myristoylated fragment mediates cell death and actin reorganization via the JNK signaling pathway.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol PAK2
Entrez
Uniprot