p66 beta Antibody

Images

 
Western Blot: p66 beta Antibody [H00057459-D01P] - Analysis of GATAD2B expression in transfected 293T cell line by GATAD2B polyclonal antibody.Lane 1: GATAD2B transfected lysate(65.30 KDa).Lane 2: Non-transfected lysate.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

p66 beta Antibody Summary

Immunogen
GATAD2B (NP_065750.1, 1 a.a. ~ 593 a.a) full-length human protein.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GATAD2B
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA
Application Notes
This antibody is useful for Western Blot

Reactivity Notes

This product is reactive against Human.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
Protein G purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for p66 beta Antibody

  • FLJ37346
  • GATA zinc finger domain containing 2B
  • GATA zinc finger domain-containing protein 2B
  • KIAA1150
  • MGC138257
  • MGC138285
  • p66/p68
  • P66beta
  • RP11-216N14.6
  • transcription repressor p66 beta component of the MeCP1 complex
  • transcriptional repressor p66-beta

Background

Methylation of cytosine at CpG dinucleotides is a common feature of many higher eukaryotic genomes (1-3). Increasing evidence indicates that recruitement of histone deacetylase complexes by methyl-CpG-binding proteins (MeCP) is a major mechanism of methylated DNA silencing. P66, a zinc finger-containing protein is one of the components of the MeCP1 complex (4). P66 and p68, the two components of MeCP1 are different forms of the same zinc finger-containing protein and are conserved from C.elegans to humans. Homologs of p66 from different organisms revealed two highly conserved regions, CR1 and CR2. While CR1 is involved in the association of p66 with other MeCP1 components, CR2 plays an important role in targeting p66 and MBD3 to specific loci (4).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol GATAD2B
Uniprot