P2Y12/P2RY12 Antibody

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Transfection Control
Transfection Positive
P2Y12 Platelet ADP Receptor detection using NLS 1544 on human megakaryocytes.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NLS1544
    • Availability
      Product Discontinued

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P2Y12/P2RY12 Antibody Summary

Immunogen
Synthetic peptide [KLH conjugated] made to the 3rd cytoplasmic loop
Localization
Cell Membrane
Specificity
P2Y12 Platelet ADP Receptor
Predicted Species
Primate (100%). Backed by our 100% Guarantee.
Clonality
Polyclonal
Host
Rabbit
Gene
P2RY12
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Positive Control
P2Y12/P2RY12 Lysate (NBL1-14038)

Reactivity Notes

Human. There is 78 % rat identity and 83 % rat homology. There is 83 % mouse identity and 89 % mouse homology.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for P2Y12/P2RY12 Antibody

  • ADPG-R
  • Gi-coupled ADP receptor HORK3
  • HORK3
  • HORK3P2Y12 platelet ADP receptor
  • P2RY12
  • P2T(AC)
  • P2Y purinoceptor 12
  • P2Y(AC)
  • P2Y(ADP)
  • P2Y(cyc)
  • P2Y12
  • P2Y12ADP-glucose receptor
  • purinergic receptor P2RY12
  • purinergic receptor P2Y, G-protein coupled, 12
  • putative G-protein coupled receptor
  • SP1999
  • SP1999G-protein coupled receptor SP1999

Background

P2Y12 is a Purinergic Receptor essential for the aggregation of blood platelets. There is evidence that mutations in P2Y12 cause a bleeding disorder, suggesting that knowledge of the P2Y12 receptor could advance the development of antiplatelet agents to treat cardiovascular diseases. Expression of P2Y12 has been reported in platelets, spinal cord, and many brain regions. ESTs for P2Y12 have been isolated from B-cell/lung/testis, brain, embryo, prostate, eye, kidney carcinoma, and colon carcinoma libraries. Cognate

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

FAQs for P2Y12/P2RY12 Antibody (NLS1544) (0)

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for P2Y12/P2RY12 Antibody (NLS1544)

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Bioinformatics

Gene Symbol P2RY12
Entrez