Western Blot: p27/Kip1 Antibody [NB100-82093] - Analysis using p27Kip1 antibody: Lane1: The extract from A2780 cells; Lane2: The extract from COLO20 degrees Cells; Lane3: The extract from COLO20 degrees Cells using ...read more
Immunohistochemistry: p27/Kip1 Antibody [NB100-82093] - Analysis of paraffin-embedded human lung carcinoma tissue using p27Kip1 (Ab-10) antibody.
27 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Cell cycle progression is regulated by cyclins and their cognate Cdks. p27 KIP 1 is a cell cycle regulatory mitotic inhibitor of cdk activity. p27 KIP 1 is a candidate tumor suppressor gene, and has been proposed to function as a possible mediator of TGF beta induced G1 arrest. p27 KIP 1 is up regulated in response to antimitogenic stimuli. The increased protein expression of p27 results in cellular arrest by binding to cyclin/Cdk complexes such as cyclin D1/Cdk4.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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