p21/CIP1/CDKN1A Antibody

Images

 
Western Blot: p21/CIP1/CDKN1A Antibody [NB100-91908] - Analysis of p21/CIP1/CDKN1A) pAb at 1:500 dilutionLane1:HEK293T whole cell lysateLane2:NIH-3T3 whole cell lysateLane3:PC12 whole cell lysate
Western Blot: p21/CIP1/CDKN1A Antibody [NB100-91908] - Analysis of extracts from Hela cell treated with EGF 200ng/ml 30 minutes.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NB100-91908
    • Availability
      Product Discontinued

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p21/CIP1/CDKN1A Antibody Summary

Immunogen
Synthetic peptide, corresponding to amino acids 100-150 of Human P21.
Specificity
p21 Cip1 (G139) antibody detects endogenous levels of p21 Cip1 protein.
Clonality
Polyclonal
Host
Rabbit
Gene
CDKN1A
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • RNA Inhibition 1:500~1:1000
Theoretical MW
21 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2)
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for p21/CIP1/CDKN1A Antibody

  • CAP20cyclin-dependent kinase inhibitor 1
  • CDK-interacting protein 1
  • CDKN1A
  • CDKN1melanoma differentiation associated protein 6
  • CIP1
  • CIP1WAF1CDK-interaction protein 1
  • cyclin-dependent kinase inhibitor 1A (p21, Cip1)
  • MDA6
  • MDA-6
  • Melanoma differentiation-associated protein 6
  • p21
  • p21CIP1
  • p21Cip1/Waf1
  • PIC1
  • SDI1DNA synthesis inhibitor
  • wild-type p53-activated fragment 1

Background

Cell cycle progression is regulated by cyclins and their cognate Cdks. p21 (WAF1/CIP1) inhibits the activity of each member of the cyclin/Cdk family, and over expression of this protein inhibits the proliferation of mammalian cells. The expression of p21 is inducible by a wide range of stress stimuli. p21 is tightly regulated at the transcriptional level by p53, and probably serves as the effector of p53 cell cycle control.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol CDKN1A
Entrez