p120-catenin Antibody

Images

 
Immunohistochemistry-Paraffin: p120-catenin Antibody [NB100-41422] - Human colon carcinoma. Antibody used at a dilution of 1:1000 (1ug/ml).
Immunoprecipitation: p120-catenin Antibody [NB100-41422] - Detection of Human CTNND1 by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: ...read more

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NB100-41422
    • Availability
      Product Discontinued

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p120-catenin Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 625 and 675 of human catenin (cadherin-associated protein), delta 1 using the numbering given in entry NP_001322.1, 1 (GeneID 1500).
Clonality
Polyclonal
Host
Rabbit
Gene
CTNND1
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Immunoprecipitation 2-5 ug/mg lysate

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for p120-catenin Antibody

  • Cadherin-associated Src substrate
  • CAS
  • catenin (cadherin-associated protein), delta 1
  • catenin delta-1
  • CTNND
  • KIAA0384P120CAS
  • p120 catenin
  • p120
  • p120(CAS)
  • p120(CTN)
  • p120cas
  • p120ctn

Background

CTNND1 is an efficient tyrosine kinase substrate implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Further, it binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway and promotes GLIS2 C-terminal cleavage.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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NB100-41422
Species: Hu
Applications: IHC, IHC-P, IP, WB (-)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CTNND1
Entrez
Uniprot