OXER1/5-oxo-ETE GPCR Antibody

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NB100-1191
    • Availability
      Product Discontinued

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OXER1/5-oxo-ETE GPCR Antibody Summary

Immunogen
Synthetic peptide: GEVSLEKEGSSQG representing the C-Terminus of the human protein (residues 411-423), according to NP_683765.
Clonality
Polyclonal
Host
Goat
Gene
OXER1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Conjugate
Unconjugated
Buffer
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Applications/Dilutions

Dilutions
  • Peptide ELISA 1:8000
Application Notes
Peptide ELISA: antibody detection limit dilution 1:32000. Western Blot: Preliminary experiments gave an approx 37kDa band in human liver lysates after 0.5ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 45.8kDa according to NP_683765.1. The 37kDa band was successfully blocked by incubation with the immunizing peptide. We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported?

Reactivity Notes

Human.

Notes

Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.

Alternate Names for OXER1/5-oxo-ETE GPCR Antibody

  • 5-oxo-ETE acid G-protein-coupled receptor 1,5-oxo-ETE G-protein coupled receptor
  • GPCR
  • GPR170
  • GPR170G-protein coupled receptor R527
  • G-protein coupled receptor 170
  • OXER1
  • oxoeicosanoid (OXE) receptor 1
  • oxoeicosanoid receptor 1
  • TG1019G-protein coupled receptor TG1019

Background

5-oxo-ETE is a potent stimulator of chemotaxis for eosinophils and neutrophils that mediate it's action via a putative G protein coupled receptor [GPCR]. The receptor is highly expressed on eosinophils and neutrophils, suggesting a key role in the inflammatory response and can also be detected in liver and kidney tissue.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for OXER1/5-oxo-ETE GPCR Antibody (NB100-1191) (0)

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Contact Information

Product PDFs

Bioinformatics

Gene Symbol OXER1
Entrez
Uniprot

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