OX40/TNFRSF4 Antibody (OX-40) Summary
Phytohemagglutinin (PHA) activated Rat Lymph Node Cells
Cell Membrane. Type I membrane protein.
NB100-65293 recognizes the OX40 antigen which is present on activated T lymphocytes that also express CD4 (1). The antigen is a glycoprotein of approximately 50kD molecular weight which is related in sequence to the low affinity Nerve Growth Factor Receptor (2). Clone OX-40 is not mitogenic, but does enhance some T cell responses (1).
Protein G purified
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Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Phosphate buffered saline pH7.4
0.09% Sodium Azide
Protein G purified
Alternate Names for OX40/TNFRSF4 Antibody (OX-40)
- ACT35 antigen
- ACT35ATC35 antigen
- CD134 antigen
- OX40 cell surface antigen
- OX40 homologue
- OX40L receptor
- OX40lymphoid activation antigene ACT35
- TAX transcriptionally-activated glycoprotein 1 receptor
- tax-transcriptionally activated glycoprotein 1 receptor
- tumor necrosis factor receptor superfamily member 4
- tumor necrosis factor receptor superfamily, member 4
- TXGP1LOX40 antigen
The OX40 receptor is also known as CD134, ACT35, and tumour necrosis factor receptor superfamily member 4. This receptor is expressed on activated CD4+ and CD8+ T cells and B cells. The OX40 receptor binds to the OX40 ligand to provide a co-stimulatory signal that is independent of CD28. Blockade of OX40-OX40 ligand interactions has been shown to ameliorate experimental EAE and inflammatory bowel disease, imply that these interactions are important in the pathogenesis of some autoimmune diseases.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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