OTUD5 Antibody Summary
The immunogen for this product maps to a region between residue 150 and 500 of human Deubiquinating Enzyme A using the numbering given in entry NP_060072.1 (GeneID 55593).
Immunogen affinity purified
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- Western Blot 1:2000-1:10000
- Immunoprecipitation 2-5 ug/mg lysate
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Packaging, Storage & Formulations
Store at 4C. Do not freeze.
TBS and 0.1% BSA
0.09% Sodium Azide
Immunogen affinity purified
Alternate Names for OTUD5 Antibody
- Deubiquitinating enzyme A
- DUBAdeubiquinating enzyme A
- EC 184.108.40.206
- OTU domain containing 5
- OTU domain-containing protein 5
This gene encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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