OTUD5 Antibody

Images

 
Western Blot: OTUD5 Antibody [NBP1-49936] - Detection of Human and Mouse DUBA by Western Blot (h&m) and Immunoprecipitation (h). Samples: Whole cell lysate from HeLa (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP ...read more

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.2 mg/ml
 

Independent Antibodies

 

Biological Strategies

     

Order Details

OTUD5 Antibody Summary

Immunogen
The immunogen for this product maps to a region between residue 150 and 500 of human Deubiquinating Enzyme A using the numbering given in entry NP_060072.1 (GeneID 55593).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
OTUD5
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1:2000-1:10000
  • Immunoprecipitation 2-5 ug/mg lysate
Theoretical MW
61 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
TBS and 0.1% BSA
Preservative
0.09% Sodium Azide
Concentration
0.2 mg/ml
Purity
Immunogen affinity purified

Alternate Names for OTUD5 Antibody

  • Deubiquitinating enzyme A
  • DKFZp761A052
  • DUBAdeubiquinating enzyme A
  • EC 3.4.19.12
  • MGC104871
  • OTU domain containing 5
  • OTU domain-containing protein 5

Background

This gene encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for OTUD5 Antibody (NBP1-49936) (0)

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Secondary Antibodies

 

Isotype Controls

Additional OTUD5 Products

OTUD5 NBP1-49936

Bioinformatics Tool for OTUD5 Antibody (NBP1-49936)

Discover related pathways, diseases and genes to OTUD5 Antibody (NBP1-49936). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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PTMs for OTUD5 Antibody (NBP1-49936)

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Bioinformatics

Gene Symbol OTUD5
Entrez
Uniprot